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Short Communication • Rev. Soc. Bras. Med. Trop. 53 • 2020 • https://doi.org/10.1590/0037-8682-0106-2019   copy

Infections and antimicrobial resistance in an adult intensive care unit in a Brazilian hospital and the influence of drug resistance on the thirty-day mortality among patients with bloodstream infections

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract

INTRODUCTION:

The present study aimed to determine the incidence of health care-associated infections (HCAIs) and identify the main resistant microorganisms in intensive care unit (ICU) patients in a Brazilian university hospital.

METHODS:

A retrospective cohort study was conducted in a Brazilian teaching hospital between 2012 and 2014.

RESULTS:

Overall, 81.2% of the infections were acquired in the ICU. The most common resistant pathogenic phenotypes in all-site and bloodstream infections were oxacillin-resistant coagulase-negative staphylococci and carbapenem-resistant Acinetobacter spp. (89.9% and 87.4%; 80.6% and 70.0%), respectively.

CONCLUSIONS:

There is an urgent need to focus on HCAIs in ICUs in Brazil.

Keywords:
Intensive care unit; Infections associated with health care; Multidrug-resistant organism; Bloodstream infections

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