This paper reports the pathological findings in seven cases of toxoplasmosis of the central nervous system. At post mortem examination a pattern of necrotizing multifocal meningoencephalitis was seen. There is a great concern about the difficulty in the clinical diagnosis of the disease when it involves the central nervous system, particularly in relation to bizarre presentations. Two of our cases had a clinical and pathological pattern resembling cerebral abscesses. The high frequency of the involvement of the choroid plexus suggests an important role for this structure in the dissemination of the infection in the central nervous system.
Toxoplasma gondii; Toxoplasmosis; Toxoplasmic encephalitis; Clinicopathological correlation