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Short Communication • Rev. Soc. Bras. Med. Trop. 54 • 2021 • https://doi.org/10.1590/0037-8682-0576-2020   copy

Preliminary evaluation of the larvicidal activity of extracts and fractions from Ocotea nutans (Nees) Mez against Aedes aegypti

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract

INTRODUCTION:

Aedes aegypti is the main vector of dengue and yellow fever. Recently, the use of plant-sourced larvicides has gained momentum.

METHODS:

The hydroethanolic extracts and fractions ofOcotea nutansleaves and stems were bioassayed to determine the larvicidal efficacy of these samples.

RESULTS:

S-HEX (hexane fraction from the crude stem extract) demonstrated high potential for controlling third-stage larvae, with an LC50 of 14.14 µg.mL-1 (concentration required to inhibit 50% of the treated larvae).

CONCLUSIONS

Extracts from O. nutans were effective against third-stage larvae ofA. aegyptiafter 24 h of exposure.

Keywords:
Ocotea nutans; Larvicidal potential; Aedes aegypti; Brazilian plant

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