A 30-year-old patient presented with persistent left inguinal pain, abdominal pain, and fever for 10 days. Abdominal examination revealed hepatomegaly, splenomegaly, and left lower quadrant and suprapubic region tenderness. An 8 cm diameter abscess was observed in abdominal ultrasonography (Figure 1). Pelvic computed tomography revealed a 69×41 mm abscess with intense inflammation in the surrounding mesenteric area extended up to the iliac vasculature (Figure 2). Brucella spp. was detected in a blood sample. The brucella tube agglutination test was found positive at 1/640. The patient had a history of consuming unpasteurized milk and milk products. Brucellosis was diagnosed based on clinical, laboratory, and radiological findings and the patient history. The patient received doxycycline (2×200 mg), rifampicin (1×600 mg), and trimethoprim-sulfamethoxazole (2×1) therapy. The fever decreased on the third day of treatment, and the abscess contracted (33×40 mm) after 14 days (Figure 3). The gynecologist did not plan surgery due to the clinical and laboratory response and the shrinkage of abscess with treatment.
Brucellosis, a zoonotic infection, is an important public health problem in many developing countries11. Centers for Disease Control (CDC). Brucellosis Reference Guide 2017. https://www.cdc.gov/brucellosis/pdf/brucellosi-reference-guide.pdf (Accessed on May 23, 2019).
https://www.cdc.gov/brucellosis/pdf/bruc...
. Tubo-ovarian abscess frequently exhibits an acute course together with genitourinary and systemic symptoms22. Bosilkovski M, Krteva L, Dimzova M, Kondova I. Brucellosis in 418 patients from the Balkan Peninsula: exposure-related differences in clinical manifestations, laboratory test results, and therapy outcome. Int J Infect Dis. 2007;11(4):342-7.. Brucellosis can affect many organs requiring a multidisciplinary approach for patient management. This etiology should be considered in differential diagnosis of patients with tubo-ovarian abscess in endemic regions.
Abdomino-pelvic computed tomography showing a 69×41 mm abscess adjacent to the iliac vascular structures.
REFERENCE
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1Centers for Disease Control (CDC). Brucellosis Reference Guide 2017. https://www.cdc.gov/brucellosis/pdf/brucellosi-reference-guide.pdf (Accessed on May 23, 2019).
» https://www.cdc.gov/brucellosis/pdf/brucellosi-reference-guide.pdf -
2Bosilkovski M, Krteva L, Dimzova M, Kondova I. Brucellosis in 418 patients from the Balkan Peninsula: exposure-related differences in clinical manifestations, laboratory test results, and therapy outcome. Int J Infect Dis. 2007;11(4):342-7.
Publication Dates
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Publication in this collection
07 Feb 2020 -
Date of issue
2020
History
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Received
25 Oct 2019 -
Accepted
11 Dec 2019