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Cases Reports • Rev. Soc. Bras. Med. Trop. 50 (06) • Nov-Dec 2017 • https://doi.org/10.1590/0037-8682-0094-2017   copy

Sofosbuvir and daclatasvir combination therapy for current hepatitis C virus genotype 4 achieves SVR: a case report of HCV genotype 4 from the Amazon

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract

Hepatitis C is a worldwide endemic disease. However, hepatitis C virus genotype 4 (HCV GT-4) has rarely been reported in Brazil. HCV GT-4 demonstrates high sustained virological response (SVR). Here, we report the case of a 62-year-old HCV GT-4 positive woman complaining of a headache, nausea, and arthralgia. The patient was treated according to the protocol for genotype 4 (12 weeks administration of 400mg sofosbuvir and 60mg daclatasvir daily) and achieved SVR. Although this is not an Amazonas autochthonous case, the presence of genotype 4 is rarely reported in the region.

Keywords:
Hepatitis C; Genotype 4; Sustained viral response

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