Influence of comorbidities on CD4+/CD8+ proportion in HIV-positive patients in Blumenau, State of Santa Catarina: a retrospective study

Abstract

INTRODUCTION:

The objective was to identify comorbidities related to HIV-positive patients in Blumenau, State of Santa Catarina.

METHODS:

A retrospective, descriptive observational design study which analyzed data from 424 patients assisted by the sexually transmitted disease/acquired immunodeficiency syndrome (STD/AIDS) Specialized Care Service (SCS).

RESULTS:

Of 424 medical records analyzed, 388 patients presented CD4⁺/CD8⁺ ratios lower than 1. The most prevalent comorbidities were smoking, depression, alcoholism, and herpes zoster infection, in males and females.

CONCLUSIONS:

The most relevant comorbidity in both genders was herpes zoster, an important marker of immunity in patients. The lowest mean was observed among patients with neurotoxoplasmosis.

Keywords:
HIV infection; Comorbidities; CD4⁺/CD8⁺ ratio.