Basic Information
The Archives of Endocrinology and Metabolism – AE&M – is the official journal of the Brazilian Society of Endocrinology and Metabolism – SBEM, which is affiliated with the Brazilian Medical Association. Edited since 1951, the AE&M aims at publishing scientific articles on themes in the basic, translational and clinical area of Endocrinology and Metabolism. The journal is available only online with fully open access, at AE&M home-page and Scielo. The journal is published on a regular basis, with six issues published per year in addition to an online version at AE&M home-page and Scielo.
ISSN 2359-3997 – printed |
AE&M is indexed on
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Intellectual Property
All the contents of the journal, except when stated, is licensed under a Creative Commons attribution type BY.
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Sponsors
The Journal has no sponsors. |
Editor-in-chief
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Coordenadora do Núcleo Interno de Regulação (NIR) HCPA
Coordenadora Grupo de Trabalho para a preparação do enfrentamento ao coronavírus HCPA
Professora Associada Depto Medicina Interna FAMED UFRGS
Email: bschaan@hcpa.edu.br
ORCID: 0000-0002-2118-8387
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Deputy Editor-in-chief
University of Notre Dame Australia, School of Medicine, Fremantle, Australia.
Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
Email: bferrazd@gmail.com
ORCID: 0000-0003-4863-2544
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Associated Editors
Faculdade de Ciências Médicas da Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, RJ, Brazil
E-mail: alessandramatheus79@yahoo.com
Instituto Nacional de Câncer (INCA), Rio de Janeiro, RJ, Brazil.
Instituto Estadual do Cérebro Paulo Niemeyer (IECPN), Rio de Janeiro, RJ, Brazil
Universidade Católica de Pelotas (UCPel), Pelotas, RS, Brazil.
Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.
Unidade de Adrenal, Divisão de Endocrinologia e Metabologia, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
Laboratory of Investigation on Metabolism and Diabetes (LIMED), Campinas, SP, Brazil
Médica da Disciplina de Endocrinologia do Departamento de Medicina da Escola Paulista de Medicina da Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Mestrado e Doutorado em Endocrinologia pela Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.
Universidade de São Paulo (USP), São Paulo, SP, Brazil.
Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.
Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. |
Editorial Commission
Universidade Federal de Santa Catarina, (UFSC), Santa Catarina, SC, Brasil
Instituto do Câncer do Estado de São Paulo (ICESP), São Paulo, SP, Brasil
Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brasil
Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (FMRPUSP), Ribeirão Preto, SP, Brasil
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brasil
Depto Medicine/University of Toronto e Leadership Sinai Centre for Diabetes/Mount Sinai Hospital
Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brasil
Universidade Federal do Paraná (UFPR), Curitiba, PR, Brasil
Universidade Federal do Paraná (UFPR), Curitiba, PR, Brasil
Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brasil
Free University Brussels, Brussels
Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brasil
Universidade de São Paulo (USP), São Paulo, SP, Brasil
Universidade Federal de Pelotas, Faculdade de Medicina – Hospital Escola, Pelotas, RS, Brasil
Faculdade de Ciências Médicas de Minas Gerais, MG, Brasil
Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil
Universidade de São Paulo (USP), São Paulo, SP, Brasil
Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brasil
Universidade Estadual de Campinas (Unicamp), Campinas, SP, Brasil
Universidade Federal do Paraná (UFPR), Curitiba, PR, Brasil
Hospital Regional de Taguatinga-Secretaria de Estado de Saúde do Distrito Federal-SES, Brasília, DF, Brasil
Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brasil
Universidade de São Paulo (USP), São Paulo, SP, Brasil
Faculdade Santa Casa Belo Horizonte, Belo Horizonte, MG, Brasil
Faculdade de Medicina de Marília (Famema), Marília – SP – Brasil
Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil
Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brasil
Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Serviço de Endocrinologia, Porto Alegre, RS, Brasil
Instituto Estadual do Cérebro Paulo Niemeyer (IECPN), Rio de Janeiro, RS, Brasil
Universidade Federal do Ceará (UFC), Fortaleza, CE, Brasil
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brasil
Universidade de São Paulo Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira, São Paulo, SP, Brasil
Departamento de Especialidades Médicas, Centro Biomédico, Departamento de Especialidades Médicas – Rio de Janeiro, RJ, Brasil
Universidade Estadual de Campinas (Unicamp), Campinas, SP, Brasil
Universidade Federal do Paraná (UFPR), Curitiba, PR, Brasil
Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil
Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brasil
Universidade Federal de Minas Gerais, Faculdade de Medicina, Departamento de Clínica Médica, Belo Horizonte, MG, Brasil
Universidade Federal do Rio Grande do Sul, Faculdade de Medicina, Programa de Pós-Graduação em Epidemiologia, Porto Alegre, RS, Brasil
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brasil
Universidade do Estado do Rio de Janeiro – Campus Vila Isabe, Rio de Janeiro, RJ, Brasil
Instituto Estadual de Diabetes e Endocrinologia Luiz Capriglione (IEDE), Rio de Janeiro, RJ, Brasil
Universidade de São Paulo (USP), São Paulo, SP, Brasil
Universidade Federal de Santa Catarina Médica Especialista em Endocrinologia e Metabologia, Florianópolis, SC, Brasil
Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil
Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brasil
Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (FMRPUSP), Ribeirão Preto, SP, Brasil
Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brasil
Faculdade de Medicina de Botucatu, Universidade Estadual Paulista (Unesp), Botucatu, SP, Brasil
Universidade Federal do Paraná(UFPR),Curitiba, PR, Brasil |
Instructions for authors
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1. EDITORIAL POLICY
The Archives of Endocrinology and Metabolism - AE&M - is an open access, streaming, peer-reviewed journal dedicated to the publication and dissemination of original research in the areas of endocrinology, diabetes, and metabolism. The journal's mission is to disseminate studies that promote the advancement of knowledge in these fields and contribute to the development of new therapies and clinical approaches. The journal is an official publication of the Brazilian Society of Endocrinology and Metabology (SBEM) and is indexed in several national and international databases, which increases the visibility and accessibility of published articles. AE&M is an important source of information and update for researchers, health professionals and students interested in endocrinology, diabetes, and metabolism.
AE&M publishes articles in several categories, as follows:
It is worth noting that AE&M accepts preprints (versions of manuscripts that have been published on preprint servers prior to peer review) as valid submissions for consideration.
The AE&M follows the recommendations of the International Committee of Medical Journal Editors (ICMJE – http://www.icmje.org/), the Committee on Publication Ethics (COPE – https://publicationethics.org/), the Council of Science Editors (CSE – https://www.councilscienceeditors.org/) and the World Association of Medical Editors (WAME – http://www.wame.org/).
Acceptance is based on originality, significance, and scientific contribution. Articles with merely propagandistic or commercial purposes will not be accepted. Articles must be submitted only in English, using easy and precise language, and avoiding the informality of colloquial language. Only manuscripts whose data are not being evaluated by other journals and/or which have not been previously published will be considered for evaluation. The contents published on AE&M are licensed under Creative Commons (CC-BY) Attribution 4.0 International (https://creativecommons.org/licenses/by/4.0/deed.en).
Authors are strongly encouraged to use appropriate reporting guidelines when preparing and submitting manuscripts to maximize transparency and reproducibility.
2. INCLUSIVE USE OF LANGUAGE
AE&M endorses the concept of people-first language. The language, in all publications, should be placed first on the person and then the disease, as the following example: subject with obesity instead of obese subject, subject with diabetes instead of diabetic subject. The same should apply to other diseases, for example: not using acromegalic, osteoporotic, hypertensive, among others. Check your text before posting to avoid unnecessary resubmission delays.
Please read below for further information: People-First Language as an important tool to fight stigma. Language has a significant impact on perceptions, behavior, motivation and, consequently, health outcomes. The contribution of the medical and scientific community is essential for the evolution of language towards reducing the stigma associated with diseases or disabilities. The “People First” movement began in 1974, focusing on people with disabilities, which may have contributed to their increasing integration into the community. People-first language was adopted by the American Psychological Association in 1992, with the aim of decreasing the focus that is placed upon the diagnosis and increasing the focus on the person. Since then, it has been widely adopted by various organizations for chronic diseases and disabilities (1). People-first language is the standard when referring to people with chronic diseases in a respectful manner, without labeling them by their illness (2). In recent years, diabetes societies have also become concerned with language choices. Diabetes Australia was the first to publish a position statement in 2012 calling for a “new language for diabetes” (3), followed by the International Diabetes Federation, which wrote a technical document on language philosophy. In 2017, the American Association of Diabetes Educators (AADE) and the American Diabetes Association (ADA) organized a task force on language in diabetes care and education and issued a document with recommendations for language related to diabetes that is respectful, inclusive, person centered, and strengths based to diabetes clinicians, diabetes educators, researchers, journal editors and authors, and other professionals who communicate about diabetes (4). Since then, the ADA’s annually published Standards of medical care in diabetes document includes a recommendation to “use language that is person centered (e.g., ‘person with diabetes’ is preferred over ‘diabetic’)” (5). When it comes to obesity, however, the scientific community is one step behind (2). A simple google scholar search using the term “diabetic people” shows about 13,500 results, while the term “people with diabetes” shows 295,000 publications. In the case of obesity, the opposite is observed: 73,300 results for “obese people” and 11,200 for “people with obesity”. Not surprisingly, obesity is a disease strongly associated with stigma in different scenarios (employment, schools, personal relationships) and it is extremely common in health care settings as well (2). In this context, individuals stigmatized due to their weight, or blamed by their health care professionals tend to gain more weight and have poorer health outcomes, according to several studies (6-8). As such, language matters and the use of people-first language could help to fight stigma, avoiding the characterization of an individual by their disease (2). Considering this, the Obesity Coalition Action has called upon authors and editors of scholarly research, scientific writing, and publications about obesity to use people-first language (9). Several organizations have already signed-on, including The Obesity Society, the World Obesity Federation, and the European Association for the Study of Obesity.
The editorial board of the Archives of Endocrinology and Metabolism, aligned with major journals that address diabetes and obesity, has decided to include the use of people-first language as a requirement for manuscript publication. We strongly believe that scientific journals should support people-fist language, to contribute to the reduction of bias and stigma. Hopefully, such a paradigm shift in scientific language will contribute to a positive change in health care education and practice.
REFERENCES
3. PREPRINT
The preprint consists of a complete version of a scientific work that has not yet been peered-reviewed. Preprints operate independently of the journal and the publishing of a preprint does not affects the peer review process. Preprints can be posted at any time during the peer review process. AE&M endorses the recommendations of the International Committee of Medical Journal Editors (ICMJE) and only accepts preprints that have the following features:
AE&M requires the completion of the Open Science Compliance Form, which must be submitted as a SUPPLEMENTARY FILE to the manuscript, and which will be accessible to reviewers. AE&M encourages editors to state any comments or opinions available regarding the manuscript in Additional Information (Form), so that editors can incorporate those comments in their considerations to the authors. If the manuscript is accepted by AE&M, authors must update the preprint article and include the following information: This is an original manuscript of an article published by Archives of Endocrinology and Metabolism on [publication date], available at: [URL and DOI]. AE&M does not accept articles deposited on preprint servers available for the digital press (Academia.edu or Research Gate) or that are released outside the scientific community before or during the submission and consideration process at AE&M. AE&M advises authors and institutions not to seek publicity and press coverage at the preprint stage, as conclusions may be watered down because of peer-review. Premature release may inaccurately reflect the results. AE&M recommends that authors and institutions only disclose press releases for articles posted as preprints after they are published. AE&M does not accept preprints of the following articles’ categories: narrative reviews, case reports, editorial/opinion/commentary articles, correspondence related to articles published in other journals or that do not include new research and laboratory protocols. AE&M requests that the preprint be listed in the ACKNOWLEDGMENTS section and that the full citation be included in the reference list.
4. RESEARCH INVOLVING HUMAN BEINGS AND EXPERIMENTAL RESEARCH
All trials involving human beings or human tissue must be in accordance with the principles explained in the Declaration of Helsinki (
Study populations - details of age, race, and sex, as relevant to the content, should be described in detail. Participating individuals must be identified only by numbers or letters, never by initials or name. Photographs of patients’ faces should only be included if they are scientifically relevant. Authors must obtain the patient’s written consent for the use of such photographs and such consent must be provided at the time of submission.
In experimental work involving animals, the standards established in the Guide for the Care and Use of Laboratory Animals (https://grants.nih.gov/grants/olaw/guide-for-the-care-and-use-of-laboratory-animals.pdf) and the Brazilian Guidelines for the Care and Use of Animals for Scientific and Didactic Purposes (DBCA), from the National Council for the Control of Animal Experimentation – CONCEA –
Manuscripts submitted to AE&M must include a statement confirming that all experimentation described was carried out in accordance with accepted standards of animal care, as described in the Ethical Guidelines. The number of animals used in each group and each experiment must be included. All research animals must be purchased and used in compliance with federal, state, and local laws and institutional regulations.
AE&M recommends that manuscripts follow the ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines, that were developed as part of an initiative by the NC3Rs to improve the design, analysis, and manuscript of investigation with animals – improving published information and minimizing unnecessary studies - https://www.nc3rs.org.uk/arrive-guidelines.
5. ETHICAL CONSIDERATIONS
AE&M supports the recommendations of the Committee on Publication Ethics (COPE), the Council of Science Editors (CSE), and the World Association of Medical Editors (WAME) regarding ethical standards of publication. AE&M is committed to ensuring integrity and ethics in the publication of scientific articles and adopts strict measures to prevent scientific misconduct.
Among the forms of misconduct, plagiarism, data fabrication, falsification, redundant or duplicate publication, violation of federal, state, or institutional rules and honorary authorship stand out. AE&M does not tolerate scientific misconduct of any kind and takes immediate action to deal with suspected cases.
The Editorial Board of AE&M uses the Similarity Check software, which allows detecting similarities in submitted materials, to prevent cases of plagiarism and duplicates. If cases of misconduct are identified, the Editorial Board of AE&M will discuss the matter and take the appropriate decisions, which may include suspending publication in the journal for a specified period, as established by the Editorial Board. The authors involved will be immediately informed of all stages of this process.
AE&M emphasizes that the responsibility for the content of the articles lies entirely with the authors, including concepts, ideas or opinions expressed in the manuscripts, as well as the origin and accuracy of the citations contained therein. The journal will not hesitate to publish errata, corrections, retractions, and apologies when necessary to correct inaccurate or misleading information.
AE&M is committed to integrity and ethics in scientific publication and continues to improve its processes and policies to ensure the quality and credibility of published articles.
Considerations on the use of Chatbots, ChatGPT in manuscripts submitted to AE&M In order to ensure the integrity and reliability of results and conclusions presented in scientific manuscripts using Chatbots or ChatGPT and to maintain public confidence in the findings and advances presented, AE&M supports WAME recommendations (https://wame.org/page3.php?id=106) regarding the ethical considerations related to the use of these technologies in scientific manuscripts, namely:
AE&M requests that authors disclose the use of generative Artificial Intelligence (AI) and AI-assisted technologies in the writing process by adding a statement at the end of the manuscript in the main text file before the list of references. The statement should be placed in a new section titled “Statement of Use of Generative AI and AI-Assisted Technologies in the Writing Process”. The statement must contain the following information: "During the process of preparation of this article, the author(s) used [TOOL/SERVICE NAME] for [PURPOSE]. After using this tool/service, the author(s) reviwed and edited the content as necessary and assume full responsibility for the content of the publication." It is important to point out that this statement is not necessary for the use of basic text revision tools, such as spelling and grammar checkers, bibliographic references, among others. If there is no use of generative AI or AI-assisted technologies in the writing process, it is not necessary to add the statement.
6. CONFLICT OF INTEREST
AE&M requires that all manuscript authors, in any category, to declare any potential sources of conflict of interest. Any interest or relationship, financial or otherwise, or personal, religious, or political beliefs that may be perceived as influencing an author’s objectivity are considered a potential source of conflict of interest. Potential sources of conflict of interest include but are not limited to: patent or stock ownership, membership of a company’s board of directors, participation in a company’s advisory board or committee, and consulting or receiving a speaker’s fee from a company. The existence of a conflict of interest does not prevent publication. If the authors have no conflict of interest to declare, it must be clear in the cover letter. It is responsibility of the corresponding author to review this policy with all authors and collectively disclose with the submission ALL relevant business relationships and any others that might be pertinent.
Manuscript Category AE&M strongly encourages authors that manuscripts meet the quality standards established by the guidelines for health research production – Enhancing the Quality and Transparency of Health Research Network (EQUATOR). EQUATOR is a directory that provides guidelines with the aim of improving the reliability of published health research literature by promoting transparent and accurate reporting. Original Article: articles that report the results of original, clinical or laboratory research. The original article must contain 3,600 words in the main text, six figures and tables, and have up to 60 references. Review Article: articles that present a critical and comprehensive review of the literature on current issues in the field of endocrinology and metabolism in the clinical or basic fields. All review articles are preferably submitted upon invitation from the AE&M and are subject to peer review. Articles in this category are ordered by the editors to authors with proven experience in the field of knowledge, or when the proposal directed by the authors in prior contact receives the approval of the editorial board. Manuscripts must contain 4,000 words, four figures or tables and up to 100 references. Brief Communication: consists of original data of sufficient importance to justify immediate publication. It is a succinct description of the confirmatory or negative results of a focused, simple, and objective trial. Objectivity and perspicuity increase the likelihood that a manuscript will be accepted for publication as a Brief Communication. The main text must contain 1,500 words, 30 references and two illustrations (tables, figures or one of each). Guidelines or Consensus: Consensus or guidelines proposed by professional societies, task forces, and other associations related to Endocrinology and Metabolism, may be published by AE&M. All manuscripts will be peer-reviewed, must be modifiable in response to criticism, and will be published only if they meet the journal’s editorial standards. The manuscript must contain 3,600 words in the main text, six figures and tables and up to 60 references. Case report: Brief communication used to present case reports, or isolated case, of clinical or scientific importance. These reports must be concise and objective. They must contain data from isolated patients or families that substantially add knowledge to the etiology, pathogenesis and natural history of the condition described. The case report must contain up to 2,000 words, four figures and tables and up to 30 references. Letter to the Editor: Letters should be brief comments related to specific points, in agreement or disagreement, with the published work, and can be presented in response to articles published in AE&M in the previous 3 editions. Original published data related to the published article are encouraged. Letters must contain 500 words and five complete references. Figures and tables cannot be included.
AE&M recommends the World Health Organization (WHO) and ICMJE clinical trial registration policies, recognizing the importance of these initiatives for the international registration and dissemination of open access clinical trial information. Thus, only clinical research articles that have received an identification number in one of the Clinical Trials Registry validated by the criteria established by WHO and by ICMJE (Brazilian Registry of Clinical Trials - REBEC) will be accepted. The registration identification number must be entered in the “Methods” section. Randomized trials should follow CONSORT guidelines. This statement provides an evidence-based approach to improving the quality of clinical trial reporting. All manuscripts describing a clinical trial must include the CONSORT Flow Diagram showing the number of participants in each intervention group, as well as a detailed description of how many patients were excluded at each phase of the data analysis. All clinical trials must be registered and made available on an open-access website. The clinical trial protocol (including the complete statistical analysis plan) must be submitted with the manuscript https://trialsjournal.biomedcentral.com/articles/10.1186/1745-6215-11-9).
As per the ICMJE recommendation, adopted by AE&M, clinical trials must contain a data sharing statement. The sharing statement must indicate: individual patient data; a data dictionary that defines each field in the dataset and the supporting documentation (e.g., statistical/analytical code); what will be made available for access; when, where and how the data is available (inform the data repository access link); types of analysis allowed; and whether there are restrictions on the use of the data. If the data cannot be shared, the reason for not sharing must be explained. For sample data sharing statements that meet ICMJE requirements, go to: http://www. icmje.org/news-and-editorials/data_sharing_june_2017.pdf
Research Data: To enable the reproducibility and reproduction of the data, AE&M encourages the deposit and sharing of research data that support the publication of the article. Data Repository is a storage space for researchers to deposit their datasets associated with their research. AE&M encourages authors who, before choosing a data repository for deposit, to consult at their institution which repository is most relevant to their research. AE&M requests that authors use FAIRsharing and re3data.org to search for a suitable repository.
Authors must select a data repository that issues a persistent identifier, preferably a DOI – Digital Object Identifier, and has established a robust preservation plan that ensures that data is preserved forever. Examples of data repositories: Dryad, Figshare, Harvard Dataverse, Mendeley Data, Open Science Framework e Zenodo.
Manuscript Preparation
The manuscript must be sent in a Microsoft Office Word file, with mandatory page layout on A4 paper (210 × 297 mm) and 2 cm margins on all sides, font Times New Roman or Arial, size 12 and 1.5 pt. spacing between lines.
All manuscripts must include a cover letter stating the importance and relevance of the manuscript. This letter should also contain the following information: whether or not there is a conflict of interest, whether the manuscript is original and has not been published elsewhere, nor is it being considered for publication elsewhere, and also include the ethics committee number (human or animal). In the case of research carried out in Brazil, the cover letter must contain the CAAE registration number generated on the Brazil platform.
Manuscripts submitted without complying with all of these items will be put on hold until completion.
AE&M uses blind review, which means that the identity of authors must be omitted from reviewers. In order to facilitate the submission process, the journal recommends that authors prepare their manuscripts in separate files as described below:
The Cover Page should be structured as follows:
It is mandatory that each author attests to have participated sufficiently in the work to assume responsibility for a significant portion of the content of the manuscript. Each of the authors must specify their contributions to the work. The corresponding author or author who submitted the work will indicate, during the submission process, the guarantee and accuracy of the integrity of all data reported in the manuscript.
AE&M recommends that authorship be based on the criteria of the ICMJE. Unrestricted co-authoring is allowed. Authorship credit should be based only on substantial contributions to:
All collaborators who do not meet the authorship criteria must be listed in the Acknowledgments section, as well as the financial support from development agencies.
Keywords: three to five descriptors in English must be included. Descriptors can be found at the following addresses: https://meshb.nlm.nih.gov/MeSHonDemand or https://meshb-prev.nlm.nih.gov/search
Manuscript Type Manuscript Preparation: the body text should not contain any information such as the name or affiliation of the authors. And it must be structured as follows:
Abstract: original articles, briefs communications and case reports must present abstracts of no more than 250 words. The abstract must contain clear and objective information about the trial in a way that can be understood without consulting the text. The abstract must include four sections that reflect the section titles of the main text. All information reported in the abstract must be originated from the manuscript. Please, use complete sentences for all sections of the abstract.
Introduction: the main goal of the introduction is to stimulate the reader’s interest in the article, offering a historical perspective and justifying its objectives.
Materials and Methods: must contain all the details of how the study was conducted, so that other investigators can evaluate and reproduce it. The origin of hormones, unusual chemicals, reagents and devices must be indicated. For modified methods, only new modifications should be described.
Results and Discussion: the Results section should briefly present the experimental data both in the text and in tables and/or figures. The repetition in the text of the results presented in the tables should be avoided. For more details on preparing tables and figures, see below. The Discussion should focus on the interpretation and meaning of the results, with concise and objective comments describing its relationship with other research in this area. In the Discussion, we must avoid repeating the data presented in Results. It may include suggestions to explain those data and must close with the conclusions.
Tables and Figures: Tables and Figures must be numbered according to the order in which they appear in the text, contain a title, and be sent in separate files. Tables must not contain data already mentioned in the text. They must be open on the sides and have a completely white background. The abbreviations used in the tables must be mentioned in alphabetical order, in the footer, with the respective forms in full. For tables taken from other sources of information or adapted (with proper permission), the credit of the source must be informed at the end of each legend in parentheses. This credit must be complete with the bibliographic reference of the source or the copyright. Likewise, the abbreviations used in the figures must be explained in the captions. Only images in JPEG format will be accepted, with minimum resolution according to the type of image, for both black and white and color images: 1200 dpi for simple black and white graphics, 300 dpi for black and White photographs and 600 dpi for color photographs. AE&M requests that the authors file the original images in their possession, as if the images submitted online present any impediment to printing, we will contact you to send us these originals.
Photographs: AE&M prefer to publish photos of unmasked patients. We encourage authors to obtain permission from patients or their families, before submitting the manuscript, for possible publication of images. If the manuscript contains identifiable patient images or protected health information, authors must submit documented authorization from the patient, or parent, guardian, or legal representative, before the material is distributed to AE&M editors, reviewers, and other staff. To identify subjects, use a numerical designation (e.g., Patient 1); do not use the initials of the name.
Sponsorship: all sources of research support (if any), as well as the project number and the responsible institution, must be declared. The role of funding agencies in designing the study and collecting, analyzing, and interpreting data and writing the manuscript should be stated in Acknowledgments.
Acknowledgments: All participants who have made substantial contributions to the manuscript (e.g., data collection, analysis, and assisting writing or editing), but who do not meet the authorship criteria, should be named with their specific contributions in Acknowledgments in the Manuscript. The conflict-of-interest statement must be included in this section. Even if the authors do not have a relevant conflict of interest to disclose, they must report it in the Acknowledgments section.
References: the references of printed and electronic documents must be standardized in accordance with the Vancouver style, prepared by the ICMJE. References must be in numerical order (in parentheses), according to the citation in the text, and listed in the same numerical order at the end of the manuscript, on a separate page.
AE&M encourages the use of the DOI, as it guarantees a permanent access link to the electronic article. For articles or texts published on the internet that do not contain the DOI, indicate the full URL address, as well as the access date on which They were accessed. Vancouver-style examples are available on the National Library of Medicine (NLM) website at Citing Medicine: https://www.ncbi.nlm.nih.gov/books/NBK7256/.
Example:
Article
Bein M, Yu OHY, Grandi SM, Frati FYE, Kandil I, Filion KB. Levothyroxine and the risk of adverse pregnancy outcomes in women with subclinical hypothyroidism: a systematic review and meta-analysis. BMC Endocr Disord. 202127;21(1):34. doi: 10.1186/s12902-021-00699-5.
Unit of Measurement: Results should be expressed using the metric system. Temperature should be expressed in Celsius degrees and time of day using the 24-hour clock (e.g., 0800 h, 1500 h).
Standard abbreviations: All abbreviations in the text must be defined immediately after the first use of the abbreviation.
Molecular Genetic Description: Use standard terminology for polymorphic variants, providing the rs numbers for all reported variants. Assay details, such as PCR primer sequences, must be described briefly together with rs numbers. The pedigree charts must be drawn up in accordance with the published standard: Bennett RL, French KS, Resta RG, Doyle DL. Standardized human pedigree nomenclature: update and assessment of the recommendations of the National Society of Genetic Counselors. J Genet Couns. 2008 Oct;17(5):424-33. doi: 10.1007/s10897-008-9169-9.
Nomenclatures: For genes, use genetic notation and symbols approved by the HUGO Gene Nomenclature Committee (HGNC) - (http://www.genenames.org/~V).
For mutations follow the naming guidelines suggested by the Human Genome Variation Society (http://www.hgvs.org/mutnomen/).
Provide and discuss the Hardy-Weinberg equilibrium data of the analyzed polymorphisms in the studied population. The calculation of Hardy-Weinberg equilibrium can help in discovering genotyping errors and their impact on analytical methods.
Provide the original frequencies of genotypes, alleles, and haplotypes.
Whenever possible, the generic name of drugs should be mentioned. When a trade name is used, it must begin with a capital letter.
Acronyms should be used sparingly and fully explained when mentioned for the first time.
Peer Review Process
AE&M adopts the review system known as single anonymized for approved manuscripts, in which the reviewers are aware of the names and affiliations of the authors, but the reports sent to the authors are anonymous. The feedback provided by the evaluators can consider the manuscript as accepted, rejected or in need of revisions, both in terms of form and content. Reviewers' opinions are appreciated by the Editor-in-Chief, who issues a final feedback report to authors.
Reviewers are experts in the field of the manuscript and are selected based on their competence and experience. They are responsible for assessing the scientific quality, originality, and relevance of the submitted work, as well as the clarity of writing and compliance with publication standards.
After the reviewers complete the review process, they issue a report with their opinions and feedback to the authors. The Editor-in-Chief uses these reports to make a final decision on publication of the manuscript. In some cases, the Editor-in-Chief may ask authors to revise the manuscript before considering publication.
The peer review process is a critical component of the article publishing process and helps to ensure the quality and credibility of the published work.
Electronic Submission
Manuscripts must be submitted and filled online in the ScholarOne system - https:// mc04.manuscriptcentral.com/aem-scielo, accompanied by:
Each document must be attached, separately, in the field indicated by the system.
To start the process, the subject responsible for the submission must previously register in the system as an author by creating/associating the ORCID register – https://orcid.org/signin. All authors must have their registration associated with an updated ORCID.
Important considerations:
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