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The evolution of purinergic receptors involved in recognition of a blood meal by hematophagous insects

Abstract

Many blood feeders use adenine nucleotides as cues for locating blood meal. Structure-activity relationship of adenine nucleotides as phagostimulants varies between closely-related species of blood feeders. It is suggested that a preexisting diverse pool of nucleotide-binding proteins present in all living cells, serves as a source of receptor proteins for the gustatory receptors involved in blood detection. It is proposed that the selection of any such nucleotide-binding protein is random.


ABSTRACT

The evolution of purinergic receptors involved in recognition of a blood meal by hematophagous insects

Rachel Galun1

Hebrew University, Hadassah Medical School, Department of Parasitology, Jerusalem, s.p

Many blood feeders use adenine nucleotides as cues for locating blood meal. Structure-activity relationship of adenine nucleotides as phagostimulants varies between closely-related species of blood feeders. It is suggested that a preexisting diverse pool of nucleotide-binding proteins present in all living cells, serves as a source of receptor proteins for the gustatory receptors involved in blood detection. It is proposed that the selection of any such nucleotide-binding protein is random.

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Publication Dates

  • Publication in this collection
    26 June 2009
  • Date of issue
    1987
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