Development and validation of the sleep assessment instrument for older adults with pain

Desenvolvimento e validação do instrumento de avaliação de sono para idosos com dor

Abstract

Background:  The co-occurrence of chronic pain and sleep disturbance contribute to a significant functional and social impact in older adults. However, there are no validated instruments to measure sleep disturbance and pain in this population that could be used to screen or diagnose individuals or monitor treatment effectiveness.

Objective:  Our aim was to develop and validate a brief, practical, and comprehensive tool to assess the impact of co-occurring pain and sleep disturbance in older adults.

Methods:  Development and validation of a measurement tool for assessing pain and sleep in older adults consisting of seven items.

Results:  We applied the “Sleep Assessment Instrument for Pain in older adults” (SAIOAP) in a sample of 100 older individuals. A Cronbach’s alpha of 0.602 indicated a moderate level of reliability, and item-total correlations of ≥0.4 for all items indicated good homogeneity. There were statistically significant correlations between the SAIOAP and sleep quality (PSQI, r=61.5), pain intensity (VNS, r=30.5), the multidimensional impacts of pain (GPM, r=40.5), depression (GEAP, r=45.5), comorbidity (r=27.9), and medication use (r=30.4). A ROC curve indicated a sensitivity of 73.2% and a specificity of 79.1% in relation to the prediction of sleep disturbances associated with pain in older adults.

Conclusions:  The SAIOAP presented adequate metric properties and was demonstrated to be a simple and practical tool for the assessment of the impact of pain on sleep in older adults.

Keywords: Sleep; Pain; Aged; Surveys and Questionnaires; Health Impact Assessment

RESUMO

Introdução:  A co-ocorrência de dor crônica e de distúrbios do sono contribuem para um impacto funcional e social negativo em idosos. Porém, o binômio dor-sono não foi explorado em relação a questionários para idosos, a fim de auxiliar na triagem, no diagnóstico ou no monitoramento da eficácia do tratamento médico.

Objetivo:  Desenvolver e validar um instrumento breve, prático e abrangente para avaliar a concorrência de condições álgicas crônicas e distúrbios de sono em idosos.

Métodos:  Estudo descritivo e qualitativo de metodologia de desenvolvimento e validação de instrumento de medida para avaliação de dor e sono em idosos, composto por sete itens. Após a fundamentação teórica, desenvolveram-se os itens do instrumento, seguidos de um estudo quantitativo (validação), em que testamos pacientes idosos com dor crônica.

Resultados:  Aplicou-se o Instrumento de Avaliação de Sono para Dor em Idosos (IASID) a uma amostra de 100 idosos. Alcançou-se o alfa de Cronbach (0,602) de boa homogeneidade por correlação item-total (≥0,4). Encontramos correlações estatisticamente significativas entre o IASID e a qualidade do sono (PSQI, r=61,5%); a intensidade da dor (NVS, r=30,5%); seus impactos (GPM, r=40,5); depressão (GEAP, r=45,5%); comorbidades (r=27,9) e uso de medicamentos (r=30,4). A curva ROC apontou sensibilidade de 73,2% e especificidade de 79,1% para predição de distúrbios do sono associados à dor crônica em idosos.

Conclusões:  O IASID apresentou propriedades métricas adequadas e demonstrou ser uma ferramenta simples e prática para a avaliação do impacto da dor no sono em idosos.

Palavras-chave: Sono; Dor; Idoso; Inquéritos e Questionários; Avaliação do Impacto na Saúde

INTRODUCTION

Sleep disorders and chronic pain are two major health issues with high incidence in older adults¹,²,³. Approximately 40% of older adults suffer from sleep disturbances causing a reduction in functional status and quality of life, besides being responsible for an increase of clinical and psychiatric comorbidities in this population⁴. Sleep disturbances (or sleep-wake disorders) involve problems with the quality, timing, and amount of sleep, which result in diurnal impairment and distress, and impairment in functioning. Sleep disturbances include sleep-related breathing disorders such as central, obstructive or mixed sleep apnea, insomnia, parasomnias, narcolepsy, REM sleep behavior disorder, excessive sleepiness, circadian rhythm disorders, and restless leg syndrome, amongst more than 80 sleep disturbances. Similarly, chronic pain is a prevalent and extremely debilitating condition, affecting more than 50% of community-dwelling older individuals and more than 80% of nursing home residents²,⁵,⁶. Chronic pain is also a risk factor for premature death and accelerated cognitive decline⁷.

There is a complex bidirectional relationship between chronic pain and sleep disorders, which has important implications for clinical management of older patients⁸,⁹,¹⁰. It is estimated that 40 to 88% of the geriatric population has coexistences of both conditions with various etiologies; for instance, migraine, musculoskeletal pain (e.g. chronic low back pain, arthralgia), fibromyalgia, osteoarthritis, and irritable bowel syndrome¹¹,¹²,¹³. Moreover, both conditions can be predictors of frailty in older adults¹⁴.

Chronic pain affects sleep in different ways, including increased insomnia, more fragmented sleep, and shorter sleep duration¹⁵,¹⁶. A recently published meta-analysis estimated a pooled prevalence of 44% of sleep disorders in patients with chronic nonmalignant pain, the most common being insomnia (72%), restless legs syndrome (32%), and obstructive sleep apnea (32%)¹⁷. Objective polysomnographic measures in individuals with chronic pain have demonstrated increased sleep onset latency, time awake after sleep onset, number of awakenings, light sleep, number of stage-shifts, respiratory-related events and periodic limb-movements, and diminished sleep efficiency and sleep duration¹⁷.

Despite the growing evidence of the sleep-pain association, sleep assessments are not routinely made in older patients with chronic pain, a measure that could help to ensure more effective treatment of pain conditions. The assessment of sleep should involve both subjective and objective measures, but this can be complex and is not always feasible. Concerning subjective sleep, there are some assessment tools which have been shown to have reliability and validity such as the Pittsburgh Sleep Quality Index (PSQI)¹⁸, the Epworth Sleepiness Scale (ESS)¹⁹, the Functional Outcomes of Sleep Questionnaire (FOSQ)²⁰, the Insomnia Severity Index (ISI)²¹, the Insomnia Symptom Questionnaire (ISQ)²², the Insomnia Impact Scale (IIS)²³, the Jenkins Sleep Evaluation Questionnaire (JSEQ)²⁴, and the Sleep Scale from the Medical Outcomes Study (MOS)²⁵. However, none of these were specifically developed to assess “sleep and pain”, and neither are they specific for older adults.

To assess sleep disturbances associated with chronic pain there are very few available tools. Only two of them have been widely used: i) the Pain and Sleep Questionnaire Three-item Index (PSQ-3), a direct measure of the impact of chronic pain on sleep²⁶, and ii) the Chronic Pain Sleep Inventory (CPSI), a 5 items tool using a 100 mm visual analogue scale²⁷. However, there is no guidance on which of these existing self-reported sleep-pain measures best capture the aspects of sleep disturbance that are most pertinent to older adults with chronic pain. Moreover, the two assessment tools were designed for the general population and not specifically for the older population. In respect of geriatric patients, the reasons for different types of pain and sleep disturbances are related to changes specifically associated with the aging process. It is important to have a tool that can be easily applied and provide the most comprehensive and detailed assessment of sleep-pain possible.

There is, therefore, a lack of validated measures of sleep disturbances in chronic pain conditions designed specifically for older adults. The creation of such a measure could help in the management of pain in aging, and optimize quality of life and functioning.

METHODS

The development and validation of the instrument to assess the impact of pain on sleep in older adults involved three steps, following a model previously described by Kline²⁸: (1) the establishment of the theoretical background/literature review, (2) a qualitative study involving the development of the tool items and the establishment of face validity, and (3) a quantitative study that involved testing the instrument with older adults with chronic pain as part of the validation process.

Ethical aspects

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee. The study protocol was approved by the Institutional Research Ethics Committee of the Universidade Federal de São Paulo (UNIFESP, CEP # 072353-2014). This article does not contain any studies with animals performed by any of the authors.

Theoretical evidence and elaboration of the tool items

Using the process suggested by Kline (1995) for the development of an instrument²⁸, we followed three steps as outlined. i) We gathered theoretical evidence through a careful thematic bibliographic review, which served to clarify the nature and range of the content related to the target construct, namely, an instrument to assess pain and sleep disorders in older adults. ii) We elaborated the tool items, taking into consideration the terms and language known to the geriatric population. In this stage, we analyzed some reliable and validated questionnaires related to sleep assessment, some involving assessment of both pain and sleep (PSQI, ESS, MOS, PSQ-3, and CPSI). The tool included seven items, demonstrating “content validity” (proved to be representative of the universe of related content). iii) The tool was then analyzed by a committee of five experts in neurology, psychiatry, gerontology, family medicine, and sleep medicine related to the subject. A minimal consensus by 80% of the experts was the criterion required to retain an item (face validity). The committee of experts stated that the older population with chronic pain conditions and sleep disturbances is clinically heterogeneous and complex, thus making the management of this entangled relationship (sleep-pain) challenging; the two conditions must be dissociated in clinical practice. Also, medications prescribed to treat pain should not affect sleep, and vice-versa, as sleep disturbances may have an adverse effect on the course of chronic pain conditions in older adults.

This process resulted in the production of the “Sleep Assessment Instrument for Older Adults with Pain” (SAIOAP) (Figure 1) — a tool consisting of seven items with “yes” or “no” answers, grouped according to the broad dimensions of sleep: initiating sleep (item 1), maintaining sleep (items 2 and 3), physical discomfort such as tiredness, exhaustion and fatigue (item 4), self-perception of sleep (item 5), daytime sleepiness (item 6), and medications used to sleep (item 7). In addition, four sub-items related to sleep latency, duration, and efficiency (in items 1 and 2) were also established for a qualitative analysis.

Figure 1
Sleep Assessment Instrument for Older Person with Pain (SAIOAP).

To evaluate the new tool, we carried out a pilot test in a sample of 15 older individuals with chronic pain. The questionnaires were completed by an investigator who read the questions and wrote down the patients’ answers. None of the test subjects found any difficulties in answering the questions so no adjustments to the tool were necessary.

Sample size calculation

The sample size was calculated for 95% power, an effect size of 0.602 with Cohens’ d of 0.50, and an α error of 0.05. For the subjective parameters (PSQI, GPM, GEAP, ADLs, and IADLs as outcomes) the required sample size was 44 participants. The sample size calculation was made using G*Power software (version 3.1.9.2, Franz Faul, Utah, USA, www.ncss.com.).

Validation of Sleep Assessment Instrument for Older Person with Pain

The validation process was also carried out according to the method described by Kline and collaborators²⁸: a) reliability analysis (internal consistency); b) validation; c) standardization of the application (implementing) process, assessment, and interpretation of the tool.

To complete the validation, a sample of 100 individuals was randomly selected from patients undergoing clinical follow up at the Geriatrics and Gerontology Department of the Universidade Federal de São Paulo. These patients complied with the inclusion criteria of being aged 60 years or older and presenting chronic pain (≥6 months). Individuals with cancer pain and cognitive impairment were excluded. All participants signed an informed consent form.

A semi-structured questionnaire was used to collect information on socio-demographic data (age, gender, race, marital status and education), self-perception of health, comorbidities, and regularly used medications, including those prescribed for sleep disorder (e.g., benzodiazepines and “z drugs”, such as Zolpidem). Based on the medication information, we classified the participants according to the number of drugs regularly used, and defined polypharmacy as the use of 5 to 9 different drugs, and excessive polypharmacy as the use of ≥10 different drugs.

Functional capacity was assessed using the Katz activities of daily living (ADLs) scale²⁸ to evaluate the abilities to undertake activities such as feeding, bathing, dressing, and leisure. The Lawton instrumental activities of daily living (IADLs) scale²⁹ was used to evaluate activities that are not necessary for fundamental functioning, but important for independent living, such as cleaning and maintaining the house and managing money. In addition, information was collected on self-perception of health status and categorized as excellent, good, regular, and poor.

The multidimensional aspects of pain were evaluated, including duration, frequency, intensity, localization, affectivity, functional impact, and others. The verbal numerical scale (VNS) of pain was applied to assess the intensity of pain³⁰ and the geriatric pain measure (GPM) was applied to assess the multidimensional aspects through domains of pain (sensory-discriminative, motivational-affective, and cognitive evaluative)³¹. According to the physiopathogenesis, pain was classified as nociceptive, neuropathic, or mixed, and according to its localization, as muscle, joint, nerve, or other pain.

To assess affectivity, an important aspect related to pain, we used the Geriatric Emotional Assessment of Pain (GEAP), which indicates little or no pain-induced depression (scores 0 to 5), moderate pain-induced depression (scores 6 to 9), and severe pain-induced depression (scores ≥10)³²,³³. For the subjective assessment of sleep, we used the Brazil Portuguese version of the PSQI, which assesses sleep quality with a sensitivity of approximately 80% and specificity of approximately 68.8%¹⁸.

Lastly, the participants were asked to answer the items of SAIOAP; we established a standard method of application to ensure uniformity in the use of the instrument.

Statistical data analysis

Data were analyzed by means of descriptive and parametric statistics using Statistical Package for the Social Sciences version 17 (SPSS Inc. Released 2008. SPSS Statistics for Windows, Version 17.0. Chicago: SPSS Inc.), Minitab 16 (Minitab 16 Statistical Software 2010. Computer software. State College, PA: Minitab, Inc. (www.minitab.com)), and Microsoft Excel (Microsoft Corporation, 2010). To evaluate the internal consistency of the instrument, Cronbach’s alpha and total-item correlation were calculated. The associations between SAIOAP and PSQI, GPM, GEAP, ENV, comorbidity, and medication were analyzed using Pearson’s correlation coefficient, and those associations related to quantitative variables, such as age range, functionality, pain characterization, self-perception of health, comorbidity, medication, GEAP, and PSQI were analyzed using the analysis of variance test (ANOVA). The Receiver Operating Characteristic (ROC) methodology was used to assess the ability of SAIOAP to predict pain in older adults with sleep disturbance. Significance was defined as p<0.05.

RESULTS

The development process described above resulted in the production of a final instrument that could be easily understood by the participants. It was very easy to apply, taking approximately five minutes.

A sample of 100 older adults with an average age of 83.1 years old and that was predominantly female (86.9%) was used in the validation process. The data from baseline measurements are shown in Table 1.

Table 1
Summary of the main characteristics of the participants (n=100).

Qualitative variables		n	%	p-value
Age (years)	60–69	3	3.0	<0.001
	70–79	24	24.2	<0.001
	≥80	72	72.2	Ref.
Gender	Female	86	86.9	<0.001
	Male	13	13.1	Ref
Race	Black	13	13.1	<0.001
	White	59	59.6	Ref.
	Brown	26	26.3	<0.001
	Asian	1	1.0	<0.001
Marital status	Married	30	30.3	<0.001
	Separated/divorced	7	7.1	<0.001
	Widowed	54	54.5	Ref.
	Single	8	8.1	<0.001
ADLs	1–2	1	1.0	<0.001
	3–4	4	4.0	<0.001
	5–6	94	94.9	Ref.
IADLs	09–15	6	6.1	<0.001
	16–20	14	14.1	<0.001
	21–25	30	30.3	0.006
	26–27	49	49.5	Ref.
Self-perception of health	Excellent	5	5.1	<0.001
	Good	26	26.3	<0.001
	Regular	61	27.3	Ref.
	Poor	7	7.1	<0.001
Polypharmacy	No polypharmacy	20	20.2	<0.001
	Polypharmacy	52	52.5	Ref.
	Severe polypharmacy	27	27.3	<0.001
Pain type	Nociceptive	77	77.8	Ref.
	Neuropathic	7	7.1	<0.001
	Mixed	15	15.2	<0.001
Pain frequency	Continuous	46	46.5	Ref.
	Intermittent	45	45.5	0.887
	Occasional	8	8.1	<0.001
Pain localization	Muscle	26	26.3	<0.001
	Joint	82	82.8	Ref.
	Nerve	20	20.2	<0.001
	Others	2	2	<0.001
Pain intensity (VNS)	Mild	4	4.0	<0.001
	Moderate	36	36.4	<0.001
	Severe	59	59.6	Ref.
Pain by GPM	Mild	7	7.1	<0.001
	Moderate	60	60.6	Ref
	Severe	32	32.3	<0.001
GEAP	No or mild depression	43	43.4	Ref
	Moderate depression	37	37.4	0.385
	Severe depression	19	19.2	<0.001
PSQI	Good sleeper	43	43.4	0.065
	Poor sleeper	56	56.6	Ref.

Quantitative variables	Mean	SD	Range
Age (years)	83.13	±7.21	64–98
Education (years)	3.84	±3.14	0–15
Comorbidity (number)	5.71	±2.29	2–11
Medication (number)	7.93	±3.04	2–14
Pain duration (months)	9.15	±9.74	0.25–50
Pain intensity (VNS)	7.10	±1.95	3–10
Pain by GPM	61.40	±19.41	4.7–99.9
GEAP	6.86	±4.59	0–21
PSQI	6.54	±3.93	1–18
SAIOAP	1.96	±1.55	1–7

• ADLs: activities of daily living; IADLs: instrumental everyday activities; SD: standard deviation; VNS: verbal numeric scale; GPM: geriatric pain measure; GEAP: Geriatric Emotional Assessment of Pain; PSQI: Pittsburgh Sleep Questionnaire Index; SAIOAP: Sleep Assessment Instrument for Older Person with Pain.

We analyzed the internal consistency of SAIOAP to test its reliability. The Cronbach’s alpha for the whole instrument was 0.602, indicating a moderate level of reliability (Table 2). The total-item correlation showed that all values had a score higher than 0.4, indicating good homogeneity between the items of the SAIOAP (suggesting that it was not necessary to delete any items) (Table 2).

Table 2
Internal consistency of Sleep Assessment Instrument for Older Person with Pain (SAIOAP) measure with Cronbach alpha and corrected total-item correlation.

SAIOAP	Corrected total-item correlation
Item 1	0.520
Item 2	0.533
Item 3	0.589
Item 4	0.580
Item 5	0.496
Item 6	0.613
Item 7	0.598
Cronbach alpha (Total)	0.602

• SAIOAP: Sleep Assessment Instrument for Older Person with Pain.

We observed statistically significant correlations between the SAIOAP and sleep quality, pain (both in respect of intensity and multidimensional aspects), independence in respect of ADLs, comorbidity, medication consumption, and depression (Table 3). The strongest correlation observed was with sleep quality (r=68.3%; p<0.001), indicating convergent construct validity of the SAIOAP.

Table 3
Correlation between Sleep Assessment Instrument for Older Person with Pain (SAIOAP) and principal variables by Pearson’s correlation.

	Correlation (r)	p-value
Sleep quality (PSQI)	68.3%	<0.001
Pain intensity (VNS)	28.5%	0.004
Multidimensional aspects of pain (GPM)	40.5%	<0.001
Depression (GEAP)	46.1%	<0.001
Comorbidity (number)	28.2%	0.005
Medication (number)	32.6%	0.001

• PSQI: Pittsburgh Sleep Quality Index; VNS: verbal numeric scale; GPM: geriatric pain measure; GEAP: geriatric emotional of pain.

The ROC curve analysis with the PSQI demonstrated that the SAIOAP had sensitivity of 73.2% and specificity of 79.1% (with an area under the curve of 0.798, p=0.046). The best cutoff point found for the SAIOAP was 1.5, therefore, two or more scores from the SAIOAP could produce a total score that predicted sleep disturbances in older adults with pain (Figure 2).

Figure 2
ROC curve for the performance of the Sleep Assessment Instrument for Older Person with Pain (SAIOAP) according to the Pittsburgh Sleep Questionnaire Index.

DISCUSSION

In the current study we developed and validated an assessment tool designed specifically for older adults with chronic pain. This is the first instrument designed to measure the pain-sleep relationship in this population. The SAIOAP is quick and easy to apply, and considers important sleep dimensions, namely, sleep onset and maintenance, physical discomfort, diurnal repercussions of sleep such as excessive daytime sleepiness, self-perception of health status, and medication used for sleep. The SAIOAP was applied in a sample of older adults whose pain intensity was mainly moderate or severe, and the average duration of experiencing pain was about nine years. In addition, the participants frequently presented pain-induced depression (more than 50% of the sample), which suggests that pain had an important affective impact in our sample. The presence of an intrinsic relationship between pain and depression is significant, and both conditions should be simultaneously treated¹⁷. This is in line with the suggestion by some authors that sleep problems need to be considered in a broader context²⁵.

We observed adequate psychometric proprieties for the SAIOAP. Foremost, content and face validity were demonstrated, respectively, by including universally representative content and by experts assessing if the content looked appropriate “on the face of it” (face validity). The other psychometric properties of the SAIOAP were shown to be good. The Cronbach’s alpha did not reach 0.7, which is generally considered the cut off for good internal consistency, and this may be related to the small number of items in the instrument. All items in the scale had scores above 0.4 which indicated very good discriminant validity³⁴. Nevertheless, the total-item correlation indicated that the assessment tool had uniform items (values all above 0.4). That is, all 7 items had moderate correlation with SAIOAP total scores³⁵. In the validation process, a statistically significant correlation was verified between the SAIOAP and several factors, particularly sleep quality (PSQI). There was also a statistically significant and positive association of SAIOAP with the uni- and multidimensional aspects of pain, pain-induced depression, comorbidities, number of medications used, and self-perception of health. The correlation with sleep quality determined the construct validity of the SAIOAP.

Our finding that sleep quality in our sample was considered poor is in accordance with the literature. Older adults tend to present poor sleep quality, with studies in the literature showing that rates of sleep disorders elderlies with pain range from 40 to 88%³⁶,³⁷. However, poor quality of sleep is not found in all older adults, and it should not be assumed to be “a normal finding”. There are many highly functional older adults that have a restorative sleep, even though it is often of objectively poorer quality compared with younger adults³⁸,³⁹. In addition, in older adults there may be age-related sleep changes such as changes in circadian rhythm (phase advance) and sleep architecture changes (e.g., shortened sleep duration, frequent awakenings, and decreased slow wave sleep). Furthermore, an increased frequency of daytime naps and time spent awake during the night could also negatively influence sleep. A lack of physical activity and sedentary behavior could also predispose individuals to more pain, increased pain perception, and reduced sleep consolidation. Contrary, pain might also predispose individuals to less activity and sedentary behavior. Therefore, although sleep disorders have multifactorial causes, sleep disorders in older adults are often attributed to pain³. Again, the homeostatic mechanisms of sleep become less robust with normal aging and added to changes in hormone secretion profiles can negatively impact the sleep-pain relationship³⁸,³⁹.

Sleep disturbance is a crucial component in the conceptual model for sleep-related problems in patients with pain. The SAIOAP was shown to have both sensitivity and specificity in relation to predicting pain in older adults with sleep disturbance, thus this tool can be used in clinical practice to screen, diagnose, and monitor the pain-sleep relationship in this specific clinical population and evaluate the effectiveness of treatments.

There are some limitations to be considered. Sleep analysis could be better determined using objective polysomnographic or actigraphy examination, but this was not possible due to the high cost and was not therefore included in the analysis. In addition, other factors such as reproducibility and predictive validity were not fully explored and will require further investigation.

The results of the present study show that the SAIOAP should be used as a direct measure of the impact of sleep in older patients with pain. This is an easy-to-apply, detailed assessment tool for the pain-sleep relationship in the older population, and the study has shown the tool to be a reliable and valid for the screening of sleep disturbances in older adults with pain. This tool could be used to identify older adults with sleep disturbances and pain, facilitating prompt targeted treatment in relation to both conditions.

The SAIOAP is an easy and short tool for researchers and health professionals to directly evaluate the impact of co-occurring pain and sleep disturbance on older adults, something that is not possible with the few currently validated measures.

• Support:
  Cristina Frange receives of a grant from the São Paulo Research Foundation (FAPESP #2018/18952-1). The sponsor had no role in the design or conduct of this research.

References

• ¹ Neikrug AB, Ancoli-Israel S. Sleep disorders in the older adult – a mini-review. Gerontology. 2010 Mar;56(2):181-9. https://doi.org/10.1159/000236900
  » https://doi.org/10.1159/000236900
• ² Helme RD, Gibson SJ. The epidemiology of pain in elderly people. Clin Geriatr Med. 2001 Aug;17(3):417-31. https://doi.org/10.1016/s0749-0690(05)70078-1
  » https://doi.org/10.1016/s0749-0690(05)70078-1
• ³ Dentino A, Medina R, Steinberg E. Pain in the elderly: identification, evaluation, and management of older adults with pain complaints and pain-related symptoms. Prim Care. 2017 Sep;44(3):519-28. https://doi.org/10.1016/j.pop.2017.04.009
  » https://doi.org/10.1016/j.pop.2017.04.009
• ⁴ Chen Q, Hayman LL, Shmerling RH, Bean JF, Leveille SG. Characteristics of chronic pain associated with sleep difficulty in older adults: the Maintenance of Balance, Independent Living, Intellect, and Zest in the Elderly (MOBILIZE) Boston study. J Am Geriatr Soc. 2011 Aug;59(8):1385-92. https://doi.org/10.1111/j.1532-5415.2011.03544.x
  » https://doi.org/10.1111/j.1532-5415.2011.03544.x
• ⁵ McCarthy LH, Bigal ME, Katz M, Derby C, Lipton RB. Chronic pain and obesity in elderly people: results from the Einstein aging study. J Am Geriatr Soc. 2009 Jan;57(1):115-9. https://doi.org/10.1111/j.1532-5415.2008.02089.x
  » https://doi.org/10.1111/j.1532-5415.2008.02089.x
• ⁶ Apinis C, Tousignant M, Arcand M, Yannick Tousignant Laflamme Y. Can adding a standardized observational tool to interdisciplinary evaluation enhance the detection of pain in older adults with cognitive impairments? Pain Med. 2014 Jan;15(1):32-41. https://doi.org/10.1111/pme.12297
  » https://doi.org/10.1111/pme.12297
• ⁷ Domenichiello AF, Ramsden CE. The silent epidemic of chronic pain in older adults. Prog Neuropsychopharmacol Biol Psychiatry. 2019 Jul;93:284-90. https://doi.org/10.1016/j.pnpbp.2019.04.006
  » https://doi.org/10.1016/j.pnpbp.2019.04.006
• ⁸ Finan PH, Goodin BR, Smith MT. The association of sleep and pain: an update and a path forward. J Pain. 2013 Dec;14(12):1539-52. https://doi.org/10.1016/j.jpain.2013.08.007
  » https://doi.org/10.1016/j.jpain.2013.08.007
• ⁹ Andersen ML, Araujo P, Frange C, Tufik S. Sleep disturbance and pain: a tale of two common problems. Chest. 2018 Nov;154(5):1249-59. https://doi.org/10.1016/j.chest.2018.07.019
  » https://doi.org/10.1016/j.chest.2018.07.019
• ¹⁰ Mathias JL, Cant ML, Burke ALJ. Sleep disturbances and sleep disorders in adults living with chronic pain: a meta-analysis. Sleep Med. 2018 Dec;52:198-210. https://doi.org/10.1016/j.sleep.2018.05.023
  » https://doi.org/10.1016/j.sleep.2018.05.023
• ¹¹ Eslami V, Zimmerman ME, Grewal T, Katz M, Lipton RB. Pain grade and sleep disturbance in older adults: evaluation the role of pain, and stress for depressed and non-depressed individuals. Int J Geriatr Psychiatry. 2016 May;31(5):450-7. https://doi.org/10.1002/gps.4349
  » https://doi.org/10.1002/gps.4349
• ¹² Blyth FM, Noguchi N. Chronic musculoskeletal pain and its impact on older people. Best Pract Res Clin Rheumatol. 2017 Apr;31(2):160-8. https://doi.org/10.1016/j.berh.2017.10.004
  » https://doi.org/10.1016/j.berh.2017.10.004
• ¹³ Onen SH, Onen F. Chronic medical conditions and sleep in the older adult. Sleep Med Clin. 2018 Mar;13(1):71-79. https://doi.org/10.1016/j.jsmc.2017.09.007
  » https://doi.org/10.1016/j.jsmc.2017.09.007
• ¹⁴ Sodhi JK, Karmarkar A, Raji M, Markides KS, Ottenbacher KJ, Al Snih S. Pain as a predictor of frailty over time among older Mexican Americans. Pain. 2020 Jan;161(1):109-13. https://doi.org/10.1097/j.pain.0000000000001711
  » https://doi.org/10.1097/j.pain.0000000000001711
• ¹⁵ Mallon L, Hetta J. A survey of sleep habits and sleeping difficulties in an elderly Swedish population. Ups J Med Sci. 1997;102(3):185-97. https://doi.org/10.3109/03009739709178940
  » https://doi.org/10.3109/03009739709178940
• ¹⁶ Paixão CM, Reichenheim ME. Uma revisão sobre instrumentos de avaliação do estado funcional do idoso. Cad Saude Publica. 2005 Feb;21(1):7-19. https://doi.org/10.1590/S0102-311X2005000100002
  » https://doi.org/10.1590/S0102-311X2005000100002
• ¹⁷ Mathias JL, Cant ML, Burke ALJ. Sleep disturbances and sleep disorders in adults living with chronic pain: a meta-analysis. Sleep Med. 2018 Dec;52:198-210. https://doi.org/10.1016/j.sleep.2018.05.023
  » https://doi.org/10.1016/j.sleep.2018.05.023
• ¹⁸ Bertolazi AN, Fagondes SC, Hoff LS, Dartora EG, da Silva Miozzo IC, de Barba ME, et al. Validation of the Brazilian Portuguese version of the Pittsburgh Sleep Quality Index. Sleep Med. 2011 Jan;12(1):70-5. https://doi.org/10.1016/j.sleep.2010.04.020
  » https://doi.org/10.1016/j.sleep.2010.04.020
• ¹⁹ Johns MW. A new method for measuring daytime sleepiness: The Epworth sleepiness scale. Sleep. 1991 Dec;14(6):540-5. https://doi.org/10.1093/sleep/14.6.540
  » https://doi.org/10.1093/sleep/14.6.540
• ²⁰ Weaver TE, Laizner AM, Evans LK, Maislin G, Chugh DK, Lyon K, et al. An instrument to measure functional status outcomes for disorders of excessive sleepiness. Sleep. 1997 Oct;20(10):835-43.
• ²¹ Morin CM, Kowatch RA, Wade JB. Behavioral management of sleep disturbances secondary to chronic pain. J Behav Ther Exp Psychiatry. 1989 Dec;20(4):295-302. https://doi.org/10.1016/0005-7916(89)90060-8
  » https://doi.org/10.1016/0005-7916(89)90060-8
• ²² Morin CM, Gibson D, Wade J. Self-reported sleep and mood disturbance in chronic pain patients. Clin J Pain. 1998 Dec;14(4):311-4. https://doi.org/10.1097/00002508-199812000-00007
  » https://doi.org/10.1097/00002508-199812000-00007
• ²³ Zammit GK, WeinerJ, Damato N, Sillup GP, McMillan CA. Quality of life in people with insomnia. Sleep. 1999;22(Suppl 2):5379-85.
• ²⁴ Ford DE, Kamerow DB. Epidemiologic study of sleep disturbances and psychiatric disorders. An opportunity for prevention? JAMA. 1989 Sep 15;262(11):1479-84. https://doi.org/10.1001/jama.262.11.1479
  » https://doi.org/10.1001/jama.262.11.1479
• ²⁵ RAND Health. Sleep scale from the Medical Outcomes Study. 1986 [accessed on Jan 11, 2020]. Available from: http://www.rand.org/health/surveys_tools/mos/mos_sleep_survey.pdf
  » http://www.rand.org/health/surveys_tools/mos/mos_sleep_survey.pdf
• ²⁶ LE Ayearst, Z Harsanyi, KJ Michalko. The Pain and Sleep Questionnaire three-item index (PSQ-3): A reliable and valid measure of the impact of pain on sleep in chronic nonmalignant pain of various etiologies. Pain Res Manag. 2012 Jul-Aug;17(4):281-90. https://doi.org/10.1155/2012/635967
  » https://doi.org/10.1155/2012/635967
• ²⁷ Kosinski M, Janagap CC, Gajria K, Schein J. Psychometric testing and validation of the chronic pain sleep inventory. Clin Ther. 2007;29 Suppl:2562-77. https://doi.org/10.1016/j.clinthera.2007.12.001
  » https://doi.org/10.1016/j.clinthera.2007.12.001
• ²⁸ Kline P. The handbook of psychological testing. London: Routledge; 1995.
• ²⁹ Katz S. Assessing self-maintenance: activities of daily living, mobility, and instrumental activities of daily living. J Am Geriatr Soc. 1983 Dec;31(12):721-7. https://doi.org/10.1111/j.1532-5415.1983.tb03391.x
  » https://doi.org/10.1111/j.1532-5415.1983.tb03391.x
• ³⁰ Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist. 1969 Autumn;9(3):179-86.
• ³¹ Melzack R, Katz R. Pain measurement in persons in pain. In: Wall PD, Melzack R, editors. Textbook of Pain. Edinburgh: Churchill Livingstone; 1999. p. 409-26.
• ³² Motta TS, Gambaro RC, Santos FC. Mensuração da dor em idosos: avaliação das propriedades psicométricas da versão em português do “Geriatric Pain Measure”. Rev Dor. 2015 Jan-Mar;16(2):136-41. https://doi.org/10.5935/1806-0013.20150026
  » https://doi.org/10.5935/1806-0013.20150026
• ³³ Almeida CBL, Felix RH, Cendoroglo MS, Santos FC. Depressão dor-induzida em idosos: validação das propriedades psicométricas da versão brasileira do “Geriatric Emotional Assessment of Pain”. Rev Assoc Med Bras. 2017 Sep;63(9):741-6. https://doi.org/10.1590/1806-9282.63.09.741
  » https://doi.org/10.1590/1806-9282.63.09.741
• ³⁴ Sneed J, Herman CM. Influence of job characteristics and organizational commitment on job satisfaction of hospital foodservice employees. J Am Diet Assoc. 1990 Aug;90(8):1072-6.
• ³⁵ Loiacono ET, Watson RT, Goodhue DL. WebQual: Webqual: a web site quality instrument. Working paper 2000-126-0, University of Georgia, Athens, GA; 2000.
• ³⁶ Pilowsky I, Crettenden I, Townley M. Sleep disturbance in pain clinic patients. Pain. 1985 Sep;23(1):27-33. https://doi.org/10.1016/0304-3959(85)90227-1
  » https://doi.org/10.1016/0304-3959(85)90227-1
• ³⁷ Tang NKY, Wright KJ, Salkovski PM. Prevelance and correlates of clinical insomnia co-occuring with chronic back pain. J Sleep Res. 2007 Mar;16(1):85-95. https://doi.org/10.1111/j.1365-2869.2007.00571.x
  » https://doi.org/10.1111/j.1365-2869.2007.00571.x
• ³⁸ Vitiello MV. Sleep in normal aging. Sleep Med Clin. 2012 Sep;7(3):539-44. https://doi.org/10.1016/j.jsmc.2012.06.007
  » https://doi.org/10.1016/j.jsmc.2012.06.007
• ³⁹ Li J, Vitiello MV, Gooneratne NS. Sleep in normal aging. Sleep Med Clin. 2018 Mar;13(1):1-11. https://doi.org/10.1016/j.jsmc.2017.09.001
  » https://doi.org/10.1016/j.jsmc.2017.09.001

Publication Dates

• Publication in this collection
  00 00 2021
• Date of issue
  Oct 2021

History

• Received
  23 Sept 2020
• Reviewed
  18 Nov 2020
• Accepted
  13 Dec 2020