Calcificação encefálica difusa: registro de um caso

Rosso, Ana L. Zuma de; Maranhão Filho, Péricles de Andrade; Oliveira, Eliane Assunção de; Novis, Sérgio A. P.

doi:10.1590/S0004-282X1992000400017

Resumos

Os autores descrevem um caso de calcificação encefálica difusa primária, não-familial, cuja primeira manifestação foi disartria. Posteriormente, desenvolveu movimentos coreoatetósicos em mãos e face, discalculia e déficit de memória. A TC de crânio revelou calcificações em hemisférios cerebrais, cerebelo e tronco cerebral.

síndrome de Fahr; calcificação dos gânglios da base; calcificação encefálica difusa

The basal ganglia calcification is known since the last century but with the new neuroimage techniques (CT scan) its diagnosis became more frequent specially in asymptomatic patients. The (authors report a case with non-familial primary diffuse encephalic calcification with exuberant calcifications on cerebral hemispheres, cerebellum and brain stem, seen on CT scan.

Fahr's syndrome; basal ganglia calcification; diffuse encephalic calcification

Diffuse encephalic calcification a case report

Calcificação encefálica difusa: registro de um caso

Ana L. Zuma de Rosso^I; Péricles de Andrade Maranhão Filho^I; Eliane Assunção de Oliveira^II; Sérgio A. P. Novis^III

^INeurologist. From the Department of Neurology, Clementino Fraga Filho University Hospital (HUCFF-UFRJ), Rio de Janeiro

^IIResident Neurologist. From the Department of Neurology, Clementino Fraga Filho University Hospital (HUCFF-UFRJ), Rio de Janeiro

^IIIHead of the Service of Neurology. From the Department of Neurology, Clementino Fraga Filho University Hospital (HUCFF-UFRJ), Rio de Janeiro

SUMMARY

The basal ganglia calcification is known since the last century but with the new neuroimage techniques (CT scan) its diagnosis became more frequent specially in asymptomatic patients. The (authors report a case with non-familial primary diffuse encephalic calcification with exuberant calcifications on cerebral hemispheres, cerebellum and brain stem, seen on CT scan.

Key words: Fahr's syndrome, basal ganglia calcification, diffuse encephalic calcification.

RESUMO

Os autores descrevem um caso de calcificação encefálica difusa primária, não-familial, cuja primeira manifestação foi disartria. Posteriormente, desenvolveu movimentos coreoatetósicos em mãos e face, discalculia e déficit de memória. A TC de crânio revelou calcificações em hemisférios cerebrais, cerebelo e tronco cerebral.

Palavras-chave: síndrome de Fahr, calcificação dos gânglios da base, calcificação encefálica difusa.

Texto completo disponível apenas em PDF.

Full text available only in PDF format.

Dra. Ana Lúcia Zuma de Rosso Rua Paissandu 159/501 - 22210 Rio de Janeiro RJ - Brasil. Fax (5521) 2673996.

1. Brannan TS, Burger AA, Chaudhary MY. Bilateral basal ganglia calcifications visualised on CT scan. J Neurol Neurosurg Psychiatry 1980, 43:403-406.
2. Cohen CR, Duchesneau FM, Weinstein MA. Calcification of the basal ganglia as visualised by computed tomography. Radiology 1980, 134:97-99.
3. Danziger A, Kalk WJ, Sandler MP, Forman M. Computer tomography in basal ganglia calcification. Clin Radiol 1980, 31:167-168.
4. Delgado-Rodrigues RN. Neurocisticercose associada a hipoparatireoidismo e doença de Fahr: relato de caso. Arq Neuropsiquiatr 1984, 42:388-391.
5. Fenelon G, Guillard A. Maladie de Fahr et calcification des noyaux gris centraux. Encycl Méd Chir, Neurologie. Paris: 1987, p 17062 M10.
6. Francis A, Freeman H. Psychiatry abnormality and brain calcification over four generations. J Nerv Ment Dis 1984. 172:166-170.
7. Harrington MG, MAcPhersen P. Mcintosh WB, Allam BF, Bone I. The significance of the incidental finding of basal ganglia calcification on computed tomography. J Neurol Neurosurg Psychiatry 1981, 44:1168-1170.
8. Herraiz J, Roquer J, Escudero D, Masó E. Meige's syndrome and bilateral pallidal calcification. J Neurol 1988. 235:384.
9. Hilton-Jone D. The significance of the incidental finding of basal ganglia calcification on computed tomography. J Neurol Neurosurg Psychiatry 1982, 45:942-943.
10. Kuroiwa Y, Mayron MS. Boiler F, Boiler M. Computed tomography visualization of extensive calcinosis in a patient with idiopathic familial basal ganglia calcification. Arch Neurol 1982, 39:603.
11. Larsen TA, Dunn KG. Jan JE, Calne DB. Dystonia and calcification of the basal ganglia. Neurology 1985, 35:533-537.
12. Menta L, Trounce JQ, Moore Jr, Young ID. Familial calcification of the basal ganglia with cerebrospinal fluid pleocytosis. J Med Genet 1986, 23:157-160.
13. Millen SJ, Pulec JL, Kane PM. Fahr's disease: an otolaryngologic perspective. Arch Otolaryngol 1982, 108:591-594.
14. Murphy MJ. Clinical correlations of CT scan-detected calcifications of the basal ganglia. Ann Neurol 1979, 6:507-511.
15. Okada J, Takeuchi K, Ohkado M, Hoshima K. Familial basal ganglia calcification visualized by computed tomography. Acta Neurol Scand 1961, 64 :273-279.
16. Pehrson P-O. Wahlgren M. Bengtsson E. Intracranial calcifications probably due to congenital Chagas disease. J Exp Med Hyg 1982, 31:449-451.
17. Puvanendran K. Low CH. Boey HK, Tan KP. Basal ganglia calcification on computed tomography scan: a clinical and radiological correlation. Acta Neurol Scand 1982, 66:309-315.
18. Raafat F. Morita M. Lau M, Taylor C-M, White RHE. Juvenile nephronophithisis with calcification of basal ganglia and pancreatic insufficiency. Arch Pathol Lab Med 1988, 112:630-633.
19. Tafani B, Boudouresques G, Turpin JC, Khalil R. Aspects actuels de la maladie de Fahr. Sem Hop Paris 1981, 57 :1815-1818.
20. Trautner RJ, Cummings JL, Read SL, Benson DF. Idiopathic basal ganglia calcification and organic mood disorder. Am J Psychiatry 1988, 145:350-353.
21. Weisinger JR, Mogollón A. Lander R, Bellorin-Font E, Riera R, Abadí I, Martínez VP. Massive cerebral calcifications associated with increased renal phosphate reabsorption. Arch Intern Med 1986, 146:473-477.

Datas de Publicação

Publicação nesta coleção
22 Fev 2011
Data do Fascículo
Dez 1992

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. Brannan TS, Burger AA, Chaudhary MY. Bilateral basal ganglia calcifications visualised on CT scan. J Neurol Neurosurg Psychiatry 1980, 43:403-406.

[2] 2. Cohen CR, Duchesneau FM, Weinstein MA. Calcification of the basal ganglia as visualised by computed tomography. Radiology 1980, 134:97-99.

[3] 3. Danziger A, Kalk WJ, Sandler MP, Forman M. Computer tomography in basal ganglia calcification. Clin Radiol 1980, 31:167-168.

[4] 4. Delgado-Rodrigues RN. Neurocisticercose associada a hipoparatireoidismo e doença de Fahr: relato de caso. Arq Neuropsiquiatr 1984, 42:388-391.

[5] 5. Fenelon G, Guillard A. Maladie de Fahr et calcification des noyaux gris centraux. Encycl Méd Chir, Neurologie. Paris: 1987, p 17062 M10.

[6] 6. Francis A, Freeman H. Psychiatry abnormality and brain calcification over four generations. J Nerv Ment Dis 1984. 172:166-170.

[7] 7. Harrington MG, MAcPhersen P. Mcintosh WB, Allam BF, Bone I. The significance of the incidental finding of basal ganglia calcification on computed tomography. J Neurol Neurosurg Psychiatry 1981, 44:1168-1170.

[8] 8. Herraiz J, Roquer J, Escudero D, Masó E. Meige's syndrome and bilateral pallidal calcification. J Neurol 1988. 235:384.

[9] 9. Hilton-Jone D. The significance of the incidental finding of basal ganglia calcification on computed tomography. J Neurol Neurosurg Psychiatry 1982, 45:942-943.

[10] 10. Kuroiwa Y, Mayron MS. Boiler F, Boiler M. Computed tomography visualization of extensive calcinosis in a patient with idiopathic familial basal ganglia calcification. Arch Neurol 1982, 39:603.

[11] 11. Larsen TA, Dunn KG. Jan JE, Calne DB. Dystonia and calcification of the basal ganglia. Neurology 1985, 35:533-537.

[12] 12. Menta L, Trounce JQ, Moore Jr, Young ID. Familial calcification of the basal ganglia with cerebrospinal fluid pleocytosis. J Med Genet 1986, 23:157-160.

[13] 13. Millen SJ, Pulec JL, Kane PM. Fahr's disease: an otolaryngologic perspective. Arch Otolaryngol 1982, 108:591-594.

[14] 14. Murphy MJ. Clinical correlations of CT scan-detected calcifications of the basal ganglia. Ann Neurol 1979, 6:507-511.

[15] 15. Okada J, Takeuchi K, Ohkado M, Hoshima K. Familial basal ganglia calcification visualized by computed tomography. Acta Neurol Scand 1961, 64 :273-279.

[16] 16. Pehrson P-O. Wahlgren M. Bengtsson E. Intracranial calcifications probably due to congenital Chagas disease. J Exp Med Hyg 1982, 31:449-451.

[17] 17. Puvanendran K. Low CH. Boey HK, Tan KP. Basal ganglia calcification on computed tomography scan: a clinical and radiological correlation. Acta Neurol Scand 1982, 66:309-315.

[18] 18. Raafat F. Morita M. Lau M, Taylor C-M, White RHE. Juvenile nephronophithisis with calcification of basal ganglia and pancreatic insufficiency. Arch Pathol Lab Med 1988, 112:630-633.

[19] 19. Tafani B, Boudouresques G, Turpin JC, Khalil R. Aspects actuels de la maladie de Fahr. Sem Hop Paris 1981, 57 :1815-1818.

[20] 20. Trautner RJ, Cummings JL, Read SL, Benson DF. Idiopathic basal ganglia calcification and organic mood disorder. Am J Psychiatry 1988, 145:350-353.

[21] 21. Weisinger JR, Mogollón A. Lander R, Bellorin-Font E, Riera R, Abadí I, Martínez VP. Massive cerebral calcifications associated with increased renal phosphate reabsorption. Arch Intern Med 1986, 146:473-477.