HIGHLIGHTS
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Neuropathic pain has a significant impact on patients’ quality of life and functionality33 Colloca L, Ludman T, Bouhassira D, Baron R, Dickenson AH, Yarnitsky D, Freeman R, Truini A, Attal N, Finnerup NB, Eccleston C, Kalso E, Bennett DL, Dworkin RH, Raja SN. Neuropathic pain. Nat Rev Dis Primers. 2017;3:17002.,55 McCarberg B, Billington R. Consequences of neuropathic pain: quality-of-life issues and associated costs. Am J Manag Care. 2006;12(9 Suppl):S263-8..
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The difficulty in diagnosing localized neuropathic pain means that patients remain without adequate treatment for months or years99 Mick G, Baron R, Correa-Illanes G, Hans G, Mayoral V, Frías X, Sintes D, Keller T. Is an easy and reliable diagnosis of localized neuropathic pain (LNP) possible in general practice? Development of a screening tool based on IASP criteria. Curr Med Res Opin. 2014;30(7):1357-66..
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The following case reports show that the use of lidocaine 5% patch allows significant reduction of pain intensity with a favorable safety and tolerability profile both in monotherapy and in the context of multimodal and long-term therapy.
ABSTRACT
BACKGROUND AND OBJECTIVES:
Neuropathic pain is defined as a pain caused by a lesion or condition that affects the somatosensory nervous system. Taking its prevalence into account, in particular post-traumatic localized neuropathic pain, and to discuss ways to manage patients with this condition, considering efficacy and tolerability of proposed treatments, this report presents three clinical cases of patients with post-traumatic localized neuropathic pain treated with 5% lidocaine transdermal patch in both monotherapy and polytherapy.
CASE REPORTS:
This study reports the cases of three female patients aged between 29 and 81 years with complaints of pain due to trauma, who were managed with 5% lidocaine transdermal patch in prolonged treatment, with a significant improvement in pain.
CONCLUSION:
According to scientific evidence, the use of 5% lidocaine transdermal patch in post-traumatic localized neuropathic pain as shown efficacy with favorable safety and tolerance. Moreover, it was possible to demonstrate that a 5% lidocaine transdermal patch in a polytherapy format has contributed to improved outcomes with no effect in treatment tolerability.
Keywords
Lidocaine; Nerve compression; Neuropathic paining; Patch testing; Transdermal patch