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Regarding the article “Application value of magnetic resonance hydrography of the inner ear in cochlear implantation” with DOI number: http://dx.doi.org/10.1590/1806-9282.66.1.74, published in Journal of the Brazilian Medical Association, 2020;66(01), page 74, authors name order, affiliation and Corresponding Author info in the article changed from:

Authors:

Quan Wang1

Hang Zhou1

Peng Wang2

Ju-Jun Xue3

Ying-Juan Chang4

Xiu-Lin Lv5

Na Wang6

Chen-Yi Sun1

Hong Jiang1

Affiliations

1. Department of Medical Imaging, Heilongjiang Provincial Hospital, Harbin, 150036, China.

2. Integrated TCM & Western Medicine Department, Heilongjiang Provincial Hospital, Harbin, 150036, China.

3. Geriatric Department of Internal Medicine, Heilongjiang Provincial Hospital, Harbin, 150036, China.

4. Central Supply Room, Heilongjiang Provincial Hospital, Harbin 150036, China.

5. Quality Control Office, Heilongjiang Provincial Hospital, Harbin 150036, China.

6. Medical Administration Division, Heilongjiang Provincial Hospital, Harbin 150036, China.

Corresponding Author

CORRESPONDING AUTHOR: Quan Wang

Department of medical imaging, Heilongjiang Provincial Hospital, n.82 of Zhongshan Road, Xiangfang District, Harbin, China - 150036

Tel: +86 451 87131061 / Fax: +86 451 87131061

E-mail: wq_doc16@163.com

To Authors

Peng Wang1#

0000-0001-8587-6076 Xi Chen2#

Hang Zhou3

Quan Wang3

Ju-Jun Xue4

Ying-Juan Chang5

Xiu-Lin Lv6

Na Wang7

Chen-Yi Sun3

Hong Jiang3

# Peng Wang and Xi Chen contributed to this paper equally, both as the first authors.

Affiliations

1.Integrated TCM & Western Medicine Department, Heilongjiang Provincial Hospital, Harbin, 150036, China

2.Department of radioimmunity, Heilongjiang Provincial Hospital, Harbin, 150036,China

3.Department of magnetic resonance imaging, Heilongjiang Provincial Hospital, Harbin, 150036, China

4.Geriatric department of Internal Medicine, Heilongjiang Provincial Hospital , Harbin, 150036,China

5.Central supply room, Heilongjiang Provincial Hospital, Harbin 150036,China

6.Quality Control Office, Heilongjiang Provincial Hospital, Harbin 150036,China

7.Medical Administration Division, Heilongjiang Provincial Hospital, Harbin 150036, China

Corresponding Author

Hang Zhou

Department of magnetic resonance imaging,

Heilongjiang Provincial Hospital, No.82 of Zhongshan Road ,Xiangfang District, Harbin 150036,China – Tel: +86 451 87131060 – Fax: +86 451 87131060

E-mail: 26276486@qq.com

Fund program: Research project of Heilongjiang provincial health and Family Planning Commission(No. 2016-541), (No:2018416), (No:2019163).

Regarding the article “Esophageal manometry in systemic sclerosis: findings and association with clinical manifestations” with DOI number: https://doi.org/10.1590/1806-9282.66.1.48 , published in Journal of the Brazilian Medical Association, 2020;66(01), page 48, figure 1 changed from:

FIGURE 1
NORMAL CONVENTIONAL ESOPHAGEAL ELECTROMANOMETRY. PERISTALTIC CONTRACTIONS IN THE ESOPHAGEAL BODY (GREEN ARROWS), NORMOTONIC LOWER ESOPHAGEAL SPHINCTER WITH ADEQUATE RELAXATION DURING SWALLOWING (RED ARROWS)

FIGURE 1
NORMAL CONVENTIONAL ESOPHAGEAL ELECTROMANOMETRY. PERISTALTIC CONTRACTIONS IN THE ESOPHAGEAL BODY (GREEN ARROWS), NORMOTONIC LOWER ESOPHAGEAL SPHINCTER WITH ADEQUATE RELAXATION DURING SWALLOWING (RED ARROWS

Regarding the article “Bronchodilator test in extreme old age: Adverse effects of short-acting beta-2 adrenergic agonists with clinical repercussion and bronchodilator response” with DOI number: http://dx.doi.org/10.1590/1806-9282.65.11.1343, published in Journal of the Brazilian Medical Association, 2019;65(11), page 1343, figure 1 and summary (in portuguese and english) changed from:

SUMMARY

OBJECTIVE: To evaluate chronological age as a limiting factor to perform the bronchodilator test, determine significant adverse effects of short-acting beta 2 agonists with clinical repercussions, and assess bronchodilator response in extreme-old-age patients who undergo the spirometry test.

METHODS: This is a cross-sectional and retrospective study. The sample was extracted from the database (spirometer and respiratory questionnaire) of a pulmonary function service. Patients over 90 years old were included in the research, and we evaluated their bronchodilator response and its significant adverse effects that may have clinical repercussions related to the bronchodilator.

RESULTS: A sample of 25 patients aged 92.12 ± 2.22 years (95% CI, 91.20 - 93.04), with a minimum age of 90 years and a maximum of 97 years and a predominance of females with 72% (18/25). The bronchodilator test was performed in 84% (21/25) of the patients. The bronchodilator response was evaluated in 19 of the 21 patients (90.47%) who underwent the bronchodilator test. Two tests did not meet the criteria of acceptability and reproducibility. No clinical adverse effects were observed with the bronchodilator medication (salbutamol) during or after the exam.

CONCLUSIONS: Chronological age is not a limiting factor for the bronchodilator test, short-acting beta-2 agonists did not present adverse effects with significant clinical repercussion and were useful in the diagnosis and therapeutic guidance of extreme-old-age patients.

KEYWORDS: Bronchodilator agents; aged; aging; respiratory function tests; Spirometry; longevity

RESUMO

OBJETIVOS: Avaliar se idade cronológica é um fator limitante para realizar prova broncodilatadora, determinar efeitos adversos significativos com repercussão clínica dos beta-2 agonistas de curta ação e avaliar a resposta broncodilatadora na espirometria, na velhice extrema.

MÉTODOS: Estudo transversal, retrospectivo. Amostra extraída do banco de dados (espirômetro e questionário respiratório) de um serviço de função pulmonar. Incluídos na pesquisa pacientes com ≥90 anos, sendo avaliados a resposta broncodilatadora e efeitos adversos significativos com repercussão clínica ao broncodilatador.

RESULTADOS: Amostra de 25 pacientes com idade de 92,12 ± 2,22 anos (IC 95%; 91,20 – 93,04), idade mínima de 90 anos e máxima de 97 anos, predominando o sexo feminino, com 72% (18/25). A prova broncodilatadora foi realizada em 84% (21/25) dos pacientes. A avaliação da resposta ao broncodilatador foi feita em 19 dos 21 pacientes (90,47%) que realizaram a prova broncodilatadora, uma vez que dois desses exames não preencheram os critérios de aceitabilidade e reprodutibilidade. A resposta broncodilatadora foi significativa em 10,52% (2/19) dos pacientes, ambos portadores de pneumopatia obstrutiva. Não foram observados efeitos adversos com repercussão clínica da medicação broncodilatadora (salbutamol) durante ou após sua realização.

CONCLUSÕES: A idade cronológica não é um fator limitante para a realização da prova broncodilatadora, os beta-2 agonistas de curta ação não apresentaram efeitos adversos com repercussão clínica significativa e foram bastante úteis para auxiliar no diagnóstico e orientação terapêutica na velhice extrema.

PALAVRAS-CHAVE: Broncodilatadores; Idoso; Envelhecimento; Testes de função respiratória; Espirometria;

FIGURE 1 (BLANK)

TO

SUMMARY

OBJECTIVE: To evaluate chronological age is a limiting factor to perform bronchodilator test,

to determine significant adverse effects that may have clinical repercussions of short-acting beta 2 agonists and to assess the bronchodilator response in fourth age patients who submit the spirometry test.

METHODS: Cross-sectional and retrospective study. The sample extracted from the database (spirometer and respiratory questionnaire) of a pulmonary function service. Patients over 87 years were included in the research and were evaluated the bronchodilator response and significant adverse effects which may occasion clinical repercussion related to bronchodilator.

RESULTS: A sample of 75 patients aged 89.34 ± 0,29 years (95% CI, 88,74 – 89,94), minimum age of 87 years and maximum of 97 years, predominance of female with 58,7% (44/75). The bronchodilator test was performed in 86.6% (65/75) of the patients. The bronchodilator response was evaluated in 63 of the 65 patients (96.92%) who underwent the bronchodilator test. The bronchodilator response was significant in 20.63% (13/63) of the patients. No clinical adverse effects were observed with bronchodilator medication (salbutamol) during or after exam.

CONCLUSIONS: Chronological age is not a limiting factor for the bronchodilator test, short-acting beta-2 agonists did not present adverse effects with significant clinical repercussion and were useful to help in diagnosis and therapeutic guidance in the fourth age group.

KEYWORDS: Bronchodilator agents; aged; aging; respiratory function tests; Spirometry; longevity

RESUMO

OBJETIVOS: Avaliar se idade cronológica é um fator limitante para realizar prova broncodilatadora, determinar efeitos adversos com repercussão clínica significativa dos Beta 2 agonistas de curta ação e avaliar a resposta broncodilatadora na espirometria, na quarta idade.

MÉTODOS: Estudo transversal, retrospectivo. Amostra extraída do banco de dados (espirometro e questionário respiratório) de um serviço de função pulmonar. Incluídos na pesquisa pacientes com ≥ 87 anos sendo avaliado a resposta broncodilatadora e efeitos adversos com repercussão clínica significativa ao broncodilatador.

RESULTADOS: Amostra de 75 pacientes com idade de 89,34 ± 0,29 anos (IC 95% 88,74 – 89,94), idade mínima de 87 anos e máxima de 97 anos, predominando o sexo feminino com 58,7 % (44 / 75). A prova broncodilatadora foi realizada em 86,6 % (65 / 75) dos pacientes. A avaliação da resposta ao broncodilatador foi feita em 63 dos 65 pacientes (96,92%) que realizaram a prova broncodilatadora. A resposta broncodilatadora foi significativa em 20,63 % (13 / 63) dos pacientes. Não foi observado efeito adversos com repercussão clínica significativa da medicação broncodilatadora (salbutamol) durante ou após sua realização.

CONCLUSÕES: A idade cronológica não é um fator limitante para realização da prova broncodilatadora, os agonistas beta-2 de curta ação não apresentaram efeitos adversos com repercussão clinica significativa e foram úteis para auxiliar no diagnóstico e orientação terapêutica, na quarta idade.

PALAVRAS-CHAVE: Broncodilatadores; Idoso; Envelhecimento; Testes de função respiratória; Espirometria;

Figure 1:

FIGURE 1
: BRONCHODILATOR TEST AND ASSESSMENT OF SIGNIFICANT RESPONSE IN THE SAMPLE

Footnote: 1Values as %. The bronchodilator test was performed on 65 patients of the general sample (n: 75); and the assessment of the bronchodilator response was conducted in 63 of the 65 patient (due to exclusions).

Publication Dates

  • Publication in this collection
    04 May 2020
  • Date of issue
    Feb 2020
Associação Médica Brasileira R. São Carlos do Pinhal, 324, 01333-903 São Paulo SP - Brazil, Tel: +55 11 3178-6800, Fax: +55 11 3178-6816 - São Paulo - SP - Brazil
E-mail: ramb@amb.org.br