Abstract
Hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory disease affecting apocrine gland-bearing areas, often leading to extensive gluteal defects after wide surgical excision. Various surgical approaches exist, including primary closure, secondary intention healing, local flaps, and skin grafting, but no single method serves as the definitive gold standard. Local flaps may be inadequate for large defects, while skin grafts are prone to contracture, potentially compromising functional and esthetic outcomes. Perforator flaps, with long pedicles and wide rotational arcs, provide a reliable alternative, allowing reconstruction of extensive defects without causing contracture, limiting range of motion, or resulting in donor site laxity, while achieving excellent cosmetic outcomes and a short postoperative recovery time. Here, we present the case of a 48-year-old male with an 8-year history of gluteal HS, who underwent wide excision resulting in a defect measuring 32 × 14 cm. Bilateral superior gluteal artery perforator (SGAP) flaps were used successfully, with the patient returning to social activities early and demonstrating excellent functional and esthetic outcomes at 5-year follow-up. The case presently reported supports perforator flaps as a safe and effective reconstructive option for large gluteal defects in HS.
Keywords
hidradenitis suppurativa; SGAP; perforator flap; gluteal reconstruction
Resumo
A hidradenite supurativa (HS) é uma doença inflamatória crônica e recorrente que acomete áreas com glândulas apócrinas e, com frequência, provoca extensos defeitos glúteos após a ampla excisão cirúrgica. Há diversas abordagens cirúrgicas, incluindo fechamento primário, cicatrização por segunda intenção, retalhos locais e enxerto de pele, mas nenhum método isolado é um padrão-ouro definitivo. Retalhos locais podem ser inadequados em defeitos extensos, enquanto enxertos de pele são propensos à contratura, com possível comprometimento dos resultados funcionais e estéticos. Retalhos perfurantes, com pedículos longos e amplos arcos de rotação, são uma alternativa confiável, permitindo a reconstrução de defeitos extensos sem causar contratura, limitar a amplitude de movimento ou gerar frouxidão na área doadora; além disso, seus resultados estéticos são excelentes e o tempo de recuperação pós-operatória é curto. Apresentamos aqui o caso de um homem de 48 anos com histórico de HS glútea há 8 anos que foi submetido à excisão ampla, o que levou ao desenvolvimento de um defeito de 32 × 14 cm. Retalhos perfurantes bilaterais da artéria glútea superior (AGS) foram utilizados com sucesso, permitindo que o paciente retornasse às atividades sociais precocemente e demonstrasse excelentes resultados funcionais e estéticos aos 5 anos de acompanhamento. Este caso corrobora o uso de retalhos perfurantes como uma opção reconstrutiva segura e eficaz para defeitos glúteos extensos decorrentes da HS.
Palavras-chave
hidradenite supurativa; AGS; retalho perfurante; reconstrução glútea
Introduction
Hidradenitis suppurativa (HS), also known as acne inversa, is a chronic, inflammatory, recurrent disease of the hair follicle, primarily affecting apocrine gland-bearing areas. It primarily affects the gluteal, perineal, axillae, and inguinal regions, which are most commonly involved.1 It presents with deep-seated, chronic nodules, sinus tracts, fistulae, and abscesses, which may result in pain, restricted mobility, functional impairment, and significant physical and psychosocial burden, thereby leading to a reduced quality of life.2 In the literature, the prevalence of HS has been reported to range between 0.05 and 4.1%, with females being more commonly affected. Hidradenitis suppurativa has a multifactorial etiology and pathogenesis; consequently, its management is challenging.3 Management strategies for HS encompass both medical and surgical approaches. Medical treatment includes topical and systemic antibiotics, intralesional and systemic corticosteroids, hormonal therapy, and immunomodulatory agents, while surgical options range from limited lesion deroofing to radical excision of affected tissue.4 Surgical options for HS include incision and drainage for acute abscesses, deroofing of sinus tracts, limited or localized excision of diseased tissue, wide excision of affected areas, and radical excision for extensive disease.5 Reconstruction following surgical excision can be achieved by primary closure, secondary intention healing, and the use of skin flaps, depending on the size and location of the defect.6 The gluteal region is frequently involved in HS, and in advanced cases, excision often results in substantial defects that pose both functional and aesthetic challenges. In these situations, the utilization of perforator flaps provides a reliable and advantageous reconstructive option.
Case Presentation
A 48-year-old male patient presented with an 8-year history of HS, which had significantly exacerbated over the preceding 1.5 years. He had previously received combination antibiotic therapy with rifampicin and clindamycin under the supervision of a dermatologist, without achieving clinical improvement.
Physical examination revealed extensive lesions involving the bilateral gluteal and sacral regions, characterized by sinus tracts, scattered abscesses, and a malodorous discharge (Fig. 1). Following wide local excision, the resulting defect measured approximately 32 × 14 cm (Fig. 2). Reconstruction was performed using bilateral superior gluteal artery perforator (SGAP) flaps, elevated from the subfascial plane. The pedicles were meticulously freed in at least 2 cm from surrounding fascia, and the flaps were transposed to cover the defect without tension or pedicle torsion. Donor sites were closed primarily (Fig. 3).
Preoperative photograph of the patient. Extensive hidradenitis suppurativa is present in the gluteal region.
On the patient's right side, a superior gluteal artery perforator flap was advanced and the right hemigluteal region was closed; on the left side, the flap was only elevated.
The extensive defects on the gluteal region are closed by transposing bilateral superior gluteal artery perforator flaps and the donor area is closed primarily.
The postoperative course was uneventful, with no complications such as wound dehiscence or venous congestion. Drains were removed on postoperative day 6, and the patient was subsequently discharged. At 5-year follow-up, the patient demonstrated excellent functional and aesthetic outcomes, with no recurrence of hidradenitis suppurativa (Fig. 4). The flaps remained fully viable, and the patient was able to perform all daily activities without limitation.
Five years postoperatively, the patient showed excellent aesthetic and functional results without recurrence.
Discussion
Multiple surgical techniques have been described for the management of HS; however, no single approach has emerged as the definitive gold standard. According to Gierek et al., local flaps are considered the gold standard for the surgical management of HS; however, they are often inadequate for covering extensive defects resulting from wide excision.7 Sugio et al. reported that skin grafts can provide superior coverage compared to flaps in some cases; however, they are prone to contracture, which may compromise both functional and esthetic outcomes.8 While primary closure remains the fastest and simplest method for defect coverage. Dietrich et al. demonstrated that perforator-based flaps, such as lateral thoracic artery perforator (LTAP) and thoracodorsal artery perforator (TDAP), can be used for axillary reconstruction in patients with hidradenitis suppurativa without causing contracture, compromising range of motion, or resulting in laxity, while also achieving excellent aesthetic outcomes.9 According to Unal et al. (2011), secondary-intention healing and skin grafting in the gluteal region can prolong patients' return to daily and social activities and are often time-consuming. Perforator flaps, by contrast, offer long pedicles and a wide rotational arc, making them highly suitable for reconstructing extensive gluteal defects.10 In the surgical management of HS, perforator flaps offer superior cosmetic outcomes, enables a short postoperative recovery time, and can be effectively utilized for the reconstruction of extensive defects, without causing contracture or compromising range of motion.11,12 In our case, an extensive gluteal defect resulting from wide excision for HS was successfully reconstructed using bilateral superior gluteal artery perforator (SGAP) flaps, allowing the patient to return to social activities early and achieving both excellent functional and cosmetic outcomes, thereby supporting the use of perforator flaps as a reliable option for large gluteal defects in similar cases.
Conclusion
Bilateral SGAP flaps provide a reliable and effective reconstructive option for extensive gluteal defects resulting from wide excision of hidradenitis suppurativa. In our case, the use of bilateral SGAP flaps enabled complete defect coverage, preservation of range of motion, avoidance of contracture, and excellent cosmetic outcomes. The patient was able to return to social activities early, demonstrating the functional and aesthetic advantages of perforator flaps in managing large gluteal HS lesions. The present case supports the broader use of perforator flaps as a safe, versatile, and reproducible technique for extensive gluteal reconstruction in HS.
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Data Availability
Data will be available upon request to the corresponding author.
References
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